Clonidine and Clindamycin hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clonidine (clonidine) and Clindamycin hydrochloride (clindamycin hydrochloride). Common drug interactions include cerebral haemorrhage among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Clonidine and Clindamycin hydrochloride. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Clonidine?

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.

What is Clindamycin hydrochloride?

Clindamycin hydrochloride has active ingredients of clindamycin hydrochloride. It is often used in tooth abscess. eHealthMe is studying from 4,257 Clindamycin hydrochloride users. Check the latest studies of Clindamycin hydrochloride.



On Jul, 08, 2026

38 people who take Clonidine and Clindamycin hydrochloride together, and have interactions are studied.

Clonidine and Clindamycin hydrochloride drug interactions.

What are the common drug interactions of Clonidine and Clindamycin Hydrochloride, by gender? *:

female:

  1. Cerebral haemorrhage (bleeding within the brain)
  2. Chills (felling of cold)
  3. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  4. Colitis pseudomembranous (antibiotic-associated diarrhoea)
  5. Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
  6. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
  7. Dermal cyst
  8. Diabetes mellitus inadequate control
  9. Diarrhoea
  10. Diplopia (double vision)

male:

  1. Chronic kidney disease
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  3. Depression
  4. Diarrhoea
  5. Dyspnoea (difficult or laboured respiration)
  6. Glomerular filtration rate decreased
  7. Hip arthroplasty
  8. Nephrolithiasis (calculi in the kidneys)
  9. Osteonecrosis (death of bone)
  10. Pericardial effusion (fluid around the heart)

What are the common drug interactions of Clonidine and Clindamycin Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Chronic kidney disease
  2. Acute generalised exanthematous pustulosis (acute febrile drug eruption)
  3. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  4. Depression
  5. Heart rate increased
  6. Juvenile myoclonic epilepsy (childhood epilepsy occurring early in morning affecting 12 to 18 years)
  7. Loss of consciousness
  8. Renal disorder (kidney disease)
  9. Renal failure (kidney dysfunction)
  10. Hospitalisation

40-49:

  1. Chronic kidney disease
  2. Bone density decreased
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  4. Tooth loss
  5. Blood creatinine increased
  6. Bone loss
  7. Glomerular filtration rate decreased
  8. Hip arthroplasty
  9. Nephrolithiasis (calculi in the kidneys)
  10. Osteonecrosis (death of bone)

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Anxiety
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  5. Back pain
  6. Breast mass
  7. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  8. Depression
  9. Dermal cyst
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Hospitalisation
  4. Infusion site discolouration
  5. Infusion site erythema (reddening of the skin at infusion site)
  6. Infusion site pain
  7. Injection site pain
  8. Oropharyngeal candidiasis (fungal infection of oropharynx)
  9. Rectal bleeding (bleeding from rectum)
  10. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 23.68%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 21.05%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 21.05%
  4. Pain: 7 people, 18.42%
  5. High Blood Cholesterol: 5 people, 13.16%
  6. Constipation: 4 people, 10.53%
  7. Diabetes: 4 people, 10.53%
  8. Inflammation: 4 people, 10.53%
  9. Cystitis Interstitial (unknown cause characterized by bladder pain): 4 people, 10.53%
  10. Infection: 3 people, 7.89%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Clonidine and Clindamycin hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clonidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Clindamycin hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clonidine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clindamycin hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on clonidine and clindamycin hydrochloride (the active ingredients of Clonidine and Clindamycin hydrochloride, respectively), and Clonidine and Clindamycin hydrochloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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