Clonidine and Librium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clonidine (clonidine) and Librium (chlordiazepoxide hydrochloride). Common drug interactions include blood glucose decreased among females and suicidal ideation among males.

The phase IV clinical study analyzes what interactions people have when they take Clonidine and Librium. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Clonidine?

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.

What is Librium?

Librium has active ingredients of chlordiazepoxide hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 2,490 Librium users. Check the latest studies of Librium.

On Jul, 06, 2026

57 people who take Clonidine and Librium together, and have interactions are studied.

Clonidine and Librium drug interactions.

What are the common drug interactions of Clonidine and Librium, by gender? *:

female:

Blood glucose decreased
Blood glucose increased
Emotional distress
Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
Hallucination, auditory (perceiving sounds without auditory stimulus)
Logorrhoea (excessive, uncontrollable, or incoherent talkativeness)
Night sweats (sweating in night)
Pyrexia (fever)
Rigors (an episode of shaking or exaggerated shivering)
Vomiting

male:

Suicidal ideation
Completed suicide (act of taking one's own life)
Hallucination (an experience involving the perception of something not present)
Injury
Neck oedema (fluid collection in neck)
Oxygen saturation decreased
Respiratory distress (difficulty in breathing)
Respiratory rate increased (excess breathing rate/min)
Tongue oedema (swelling of tongue)
Abdominal discomfort

What are the common drug interactions of Clonidine and Librium, by age (0-1 to 60+)? *:

0-1:

Aortic valve disease mixed
Attention deficit/hyperactivity disorder
Cardiac murmur (an heart sound in valve abnormality)
Deafness
Depression
Developmental delay
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Hypertrophic cardiomyopathy (a condition in which the heart muscle becomes abnormally thick)
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Pectus carinatum (pigeon chest, is a deformity of the chest)

2-9:

n/a

10-19:

n/a

20-29:

Suicidal ideation
Blood pressure decreased
Heart rate decreased
Cardiac disorder
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Hypoaesthesia (reduced sense of touch or sensation)
Pain in extremity
Palpitations (feelings or sensations that your heart is pounding or racing)

30-39:

Arthralgia (joint pain)
Depression
Pain
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Agitation (state of anxiety or nervous excitement)
Asthma
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Depressed level of consciousness
Dizziness

40-49:

Suicide attempt
Abscess (pus)
Asthma
Cellulitis (infection under the skin)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes mellitus inadequate control
Diabetic eye disease
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Infection

50-59:

Abdominal discomfort
Abdominal distension
Abdominal pain upper
Asthenia (weakness)
Blood testosterone decreased
Decreased appetite
Dysgeusia (disorder of the sense of taste)
Dyspepsia (indigestion)
Fatigue (feeling of tiredness)
Hypophagia (reduced food intake)

60+:

Multiple injuries
Pain
Presyncope
Social problem
Weight decreased
Chronic kidney disease
Renal failure (kidney dysfunction)
Abdominal discomfort
Abdominal pain
Abscess (pus)

What are the existing conditions these people have? *

Pain: 6 people, 10.53%
Drug Dependence: 6 people, 10.53%
Panic Disorder: 5 people, 8.77%
Depression: 4 people, 7.02%

* Approximation only. Some reports may have incomplete information.

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