Clopidogrel and Depakote drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clopidogrel (clopidogrel) and Depakote (divalproex sodium). Common drug interactions include renal failure acute among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Clopidogrel and Depakote. It is created by eHealthMe based on reports of 99 people who take the same drugs from the FDA, and is updated regularly.

What is Clopidogrel?

Clopidogrel has active ingredients of clopidogrel. It is often used in blood clots. eHealthMe is studying from 92,160 Clopidogrel users. Check the latest studies of Clopidogrel.

What is Depakote?

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 55,581 Depakote users. Check the latest studies of Depakote.

On Jul, 09, 2026

99 people who take Clopidogrel and Depakote together, and have interactions are studied.

Clopidogrel and Depakote drug interactions.

What are the common drug interactions of Clopidogrel and Depakote, by gender? *:

female:

Renal failure acute (rapid kidney dysfunction)
Vertigo
Pain in extremity
Arterial thrombosis (formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system)
Atrioventricular block complete (heart block complete)
Cerebral haemorrhage (bleeding within the brain)
Dysarthria (speech disorder)
Erosive oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time)
Hemiparesis (weakness on one side of the body)
Hypotension (abnormally low blood pressure)

male:

Asthenia (weakness)
Dizziness
Pneumonia
Tremor (trembling or shaking movements in one or more parts of your body)
Blood glucose fluctuation
Cardiac failure
Chronic kidney disease
Contusion (a type of hematoma of tissue in which capillaries)
Depression
Dyskinesia (abnormality or impairment of voluntary movement)

What are the common drug interactions of Clopidogrel and Depakote, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain
Alcohol abuse
Arteriosclerosis (thickening and hardening of arteries)
Asthenia (weakness)
Borderline personality disorder
Chest pain
Cholecystitis (infection of gallbladder)
Death
Dependent personality disorder
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)

40-49:

Suicidal ideation
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Chronic kidney disease
Gait disturbance
Hemiplegia (paralysis of one side of the body)
Hyperglycaemia (high blood sugar)
Ill-defined disorder
Joint swelling
Pain in extremity

50-59:

Cardiac arrest
Cardiomyopathy (weakening of the heart muscle)
Chest pain
Cholecystitis (infection of gallbladder)
Chronic kidney disease
Confusional state
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Disturbance in social behaviour
Drug ineffective

60+:

Chronic kidney disease
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac arrest
Gastric ulcer (stomach ulcer)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Injury
Oropharyngeal pain
Polycythaemia (proportion of blood volume that is occupied by red blood cells increases)

What are the existing conditions these people have? *

High Blood Pressure: 21 people, 21.21%
High Blood Cholesterol: 18 people, 18.18%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 15.15%
Pain: 12 people, 12.12%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 8 people, 8.08%
Insomnia (sleeplessness): 8 people, 8.08%
Depression: 8 people, 8.08%
Infection: 7 people, 7.07%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 7.07%
Acne (skin problems that cause pimples): 6 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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