Clopidogrel and Nintedanib drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clopidogrel (clopidogrel) and Nintedanib (nintedanib). Common drug interactions include atrial fibrillation among females and epistaxis among males.
The phase IV clinical study analyzes what interactions people have when they take Clopidogrel and Nintedanib. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Clopidogrel?
Clopidogrel has active ingredients of clopidogrel. It is often used in blood clots. eHealthMe is studying from 92,160 Clopidogrel users. Check the latest studies of Clopidogrel.
What is Nintedanib?
Nintedanib has active ingredients of nintedanib. eHealthMe is studying from 1,514 Nintedanib users. Check the latest studies of Nintedanib.
12 people who take Clopidogrel and Nintedanib together, and have interactions are studied.

What are the common drug interactions of Clopidogrel and Nintedanib, by gender? *:
female:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Acute myocardial infarction (acute heart attack)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Respiratory failure (inadequate gas exchange by the respiratory system)
male:
- Epistaxis (bleed from the nose)
- Fatigue (feeling of tiredness)
- Hepatocellular carcinoma (liver cancer)
- Idiopathic pulmonary fibrosis (chronic lung disease)
- Lung cancer metastatic (lung cancer spreads to other parts)
- Pneumomediastinum (air is present in the mediastinum)
- Pulmonary embolism (blockage of the main artery of the lung)
- Sputum increased
- General physical health deterioration (weak health status)
- Hypophagia (reduced food intake)
What are the common drug interactions of Clopidogrel and Nintedanib, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Colitis ulcerative (inflammation of colon with ulcer)
- Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
- Lung cancer metastatic (lung cancer spreads to other parts)
- Pneumomediastinum (air is present in the mediastinum)
60+:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Acute myocardial infarction (acute heart attack)
- Dyspnoea (difficult or laboured respiration)
- Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
- Haemorrhage intracranial (bleeding within the skull)
- Hepatocellular carcinoma (liver cancer)
- Idiopathic pulmonary fibrosis (chronic lung disease)
- Sputum increased
- Subdural haemorrhage (bleeding between the skull and the surface of the brain)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
What are the existing conditions these people have? *
- Lung Cancer - Non-Small Cell (lung cancer): 3 people, 25.00%
- Interstitial Lung Disease: 3 people, 25.00%
- High Blood Pressure: 3 people, 25.00%
- Sleep Disorder: 2 people, 16.67%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 16.67%
- Idiopathic Pulmonary Fibrosis (chronic lung disease): 2 people, 16.67%
- High Blood Cholesterol: 2 people, 16.67%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 16.67%
- Gastritis (inflammation of stomach): 2 people, 16.67%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 16.67%
* Approximation only. Some reports may have incomplete information.
Do you take Clopidogrel and Nintedanib?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Clopidogrel (92,160 reports)
- Nintedanib (1,514 reports)
Browse all drug interactions of Clopidogrel and Nintedanib:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clopidogrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Nintedanib:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clopidogrel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nintedanib and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lai SW, Lin CL, Liao KF, "Actively using clopidogrel correlates with an increased risk of acute pancreatitis in Taiwan", International journal of cardiology, 2015 Mar .
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
- Lai SW, Lin CL, Liao KF, "Actively using clopidogrel correlates with an increased risk of acute pancreatitis in Taiwan", International journal of cardiology, 2015 Mar .
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on clopidogrel and nintedanib (the active ingredients of Clopidogrel and Nintedanib, respectively), and Clopidogrel and Nintedanib (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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