Clopidogrel and Xiaflex drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clopidogrel (clopidogrel) and Xiaflex (collagenase clostridium histolyticum). Common drug interactions include drug ineffective among females and drug ineffective among males.
The phase IV clinical study analyzes what interactions people have when they take Clopidogrel and Xiaflex. It is created by eHealthMe based on reports of 7 people who take the same drugs from the FDA, and is updated regularly.
What is Clopidogrel?
Clopidogrel has active ingredients of clopidogrel. It is often used in blood clots. eHealthMe is studying from 92,160 Clopidogrel users. Check the latest studies of Clopidogrel.
What is Xiaflex?
Xiaflex has active ingredients of collagenase clostridium histolyticum. eHealthMe is studying from 5,177 Xiaflex users. Check the latest studies of Xiaflex.
7 people who take Clopidogrel and Xiaflex together, and have interactions are studied.

What are the common drug interactions of Clopidogrel and Xiaflex, by gender? *:
female:
- Drug ineffective
- Injection site pain
male:
- Drug ineffective
- Contusion (a type of hematoma of tissue in which capillaries)
- Peyronie's disease (bent penis)
- Post procedural swelling
- Injection site swelling
- Swelling
- Drug effect decreased
- Erectile dysfunction
- Injection site bruising
- Injection site pain
What are the common drug interactions of Clopidogrel and Xiaflex, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Injection site pain
- Injection site paraesthesia (abnormal skin sensations at injection site)
- Injection site swelling
60+:
- Swelling
- Contusion (a type of hematoma of tissue in which capillaries)
- Drug effect decreased
- Drug ineffective
- Injection site pain
* Approximation only. Some reports may have incomplete information.
Do you take Clopidogrel and Xiaflex?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Clopidogrel (92,160 reports)
- Xiaflex (5,177 reports)
Browse all drug interactions of Clopidogrel and Xiaflex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Clopidogrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Xiaflex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clopidogrel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Xiaflex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lai SW, Lin CL, Liao KF, "Actively using clopidogrel correlates with an increased risk of acute pancreatitis in Taiwan", International journal of cardiology, 2015 Mar .
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
- Lai SW, Lin CL, Liao KF, "Actively using clopidogrel correlates with an increased risk of acute pancreatitis in Taiwan", International journal of cardiology, 2015 Mar .
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on clopidogrel and collagenase clostridium histolyticum (the active ingredients of Clopidogrel and Xiaflex, respectively), and Clopidogrel and Xiaflex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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