Clopra and Bumex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clopra (metoclopramide hydrochloride) and Bumex (bumetanide). Common drug interactions include chest pain among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Clopra and Bumex. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Clopra?

Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.

What is Bumex?

Bumex has active ingredients of bumetanide. It is often used in swelling. eHealthMe is studying from 9,210 Bumex users. Check the latest studies of Bumex.

On Jul, 06, 2026

79 people who take Clopra and Bumex together, and have interactions are studied.

What are the common drug interactions of Clopra and Bumex, by gender? *:

female:

Chest pain
Pain
Anxiety
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Fall
Oedema (fluid collection in tissue)
Pulmonary oedema (fluid accumulation in the lungs)
Depression

male:

Cardiac failure congestive
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematoma (collection of blood outside the blood vessels)
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
Hepatic failure (liver failure)
Liver disorder (liver diseases)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Septic shock (shock due to blood infection)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

What are the common drug interactions of Clopra and Bumex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Metapneumovirus infection (infection with human metapneumovirus)
Respiratory failure (inadequate gas exchange by the respiratory system)

10-19:

n/a

20-29:

Abdominal pain upper
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood glucose increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Cardiomyopathy (weakening of the heart muscle)
Chest discomfort

30-39:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Nephrolithiasis (calculi in the kidneys)
Nephropathy (damage to or disease of a kidney)
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

40-49:

Fatigue (feeling of tiredness)
Dyspnoea (difficult or laboured respiration)
Diarrhoea
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Impaired gastric emptying
Fall
Vomiting
Chronic kidney disease
Renal failure (kidney dysfunction)

50-59:

Pulmonary hypertension (increase in blood pressure in the lung artery)
Septic shock (shock due to blood infection)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pneumonia
Serratia bacteraemia (bacterial blood infection)
Staphylococcal bacteraemia (a bacterial infection of blood)
Thrombocytopenia (decrease of platelets in blood)
Thrombosis (formation of a blood clot inside a blood vessel)
Aortic thrombosis (formation of a blood clot inside aorta)

60+:

Chronic kidney disease
Death
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood glucose increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure congestive
Diarrhoea
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 17 people, 21.52%
Pain: 15 people, 18.99%
High Blood Pressure: 13 people, 16.46%
Diabetes: 10 people, 12.66%
Headache (pain in head): 9 people, 11.39%
Stress And Anxiety: 7 people, 8.86%
Blood Glucose Decreased: 5 people, 6.33%
Depression: 5 people, 6.33%
Urinary Tract Infection: 5 people, 6.33%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 5 people, 6.33%

* Approximation only. Some reports may have incomplete information.

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