Clopra and Cayston drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clopra (metoclopramide hydrochloride) and Cayston (aztreonam). Common drug interactions include fatigue among females and infective pulmonary exacerbation of cystic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Clopra and Cayston. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Clopra?

Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.

What is Cayston?

Cayston has active ingredients of aztreonam. It is often used in cystic fibrosis. eHealthMe is studying from 5,310 Cayston users. Check the latest studies of Cayston.



On Jul, 07, 2026

24 people who take Clopra and Cayston together, and have interactions are studied.

Clopra and Cayston drug interactions.

What are the common drug interactions of Clopra and Cayston, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Headache (pain in head)
  3. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  4. Bronchopulmonary aspergillosis allergic (allergic lung disorder caused by aspergillus fungi)
  5. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  6. Somnolence (a state of near-sleep, a strong desire for sleep)
  7. Asthenia (weakness)
  8. Back pain
  9. Constipation
  10. Decreased appetite

male:

  1. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  2. Dyspnoea (difficult or laboured respiration)
  3. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  4. Night sweats (sweating in night)
  5. Productive cough
  6. Pruritus (severe itching of the skin)
  7. Pseudomonas test positive
  8. Pyrexia (fever)
  9. Secretion discharge
  10. Sputum discoloured

What are the common drug interactions of Clopra and Cayston, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Bronchopulmonary aspergillosis allergic (allergic lung disorder caused by aspergillus fungi)
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Fatigue (feeling of tiredness)
  4. Headache (pain in head)
  5. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  6. Somnolence (a state of near-sleep, a strong desire for sleep)

20-29:

  1. Abdominal pain upper
  2. Chest discomfort
  3. Cough
  4. Diarrhoea
  5. Dyspnoea (difficult or laboured respiration)
  6. Flatulence (flatus expelled through the anus)
  7. Headache (pain in head)
  8. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  9. Lung disorder (lung disease)
  10. Pneumonia

30-39:

  1. Asthenia (weakness)
  2. Decreased appetite
  3. Dyspnoea (difficult or laboured respiration)
  4. Headache (pain in head)
  5. Chest discomfort
  6. Chest pain
  7. Cough
  8. Diarrhoea
  9. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  10. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)

40-49:

  1. Pulmonary hypertension (increase in blood pressure in the lung artery)
  2. Respiration (transport of oxygen from the outside air to the cells within tissues)
  3. Right ventricular failure (right half of the heart fails to work)
  4. Weight decreased
  5. Bronchial secretion retention
  6. Decreased appetite
  7. Dyspnoea (difficult or laboured respiration)
  8. Haemoglobin decreased
  9. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  10. Oxygen saturation decreased

50-59:

n/a

60+:

  1. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  2. Nasopharyngitis (inflammation of the nasopharynx)

What are the existing conditions these people have? *

  1. Cough: 8 people, 33.33%
  2. Wheezing (a high-pitched whistling sound made while you breath): 7 people, 29.17%
  3. Constipation: 7 people, 29.17%
  4. Cystic Fibrosis Lung (fibrosis with cyst in the lung): 7 people, 29.17%
  5. Muscle Spasms (muscle contraction): 6 people, 25.00%
  6. Bacterial Infection: 6 people, 25.00%
  7. Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 6 people, 25.00%
  8. Cystic Fibrosis Pancreatic (fibrosis with cyst in the pancreas): 6 people, 25.00%
  9. Depression: 6 people, 25.00%
  10. Faeces Hard: 6 people, 25.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Clopra and Cayston:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clopra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cayston:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clopra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cayston and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on metoclopramide hydrochloride and aztreonam (the active ingredients of Clopra and Cayston, respectively), and Clopra and Cayston (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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