Clopra and Cyramza drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clopra (metoclopramide hydrochloride) and Cyramza (ramucirumab). Common drug interactions include lung neoplasm malignant among females and febrile neutropenia among males.
The phase IV clinical study analyzes what interactions people have when they take Clopra and Cyramza. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Clopra?
Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.
What is Cyramza?
Cyramza has active ingredients of ramucirumab. eHealthMe is studying from 4,052 Cyramza users. Check the latest studies of Cyramza.
15 people who take Clopra and Cyramza together, and have interactions are studied.

What are the common drug interactions of Clopra and Cyramza, by gender? *:
female:
- Lung neoplasm malignant (cancer tumour of lung)
- Back pain
- Decreased immune responsiveness
- Drug ineffective
- Flushing (the warm, red condition of human skin)
- Hyperhidrosis (abnormally increased sweating)
- Hypoxia (low oxygen in tissues)
- Malignant neoplasm progression (cancer tumour came back)
- Myelosuppression (a decrease in the production of blood cells)
- Nausea (feeling of having an urge to vomit)
male:
- Febrile neutropenia (fever with reduced white blood cells)
- Pneumonia
- Vertigo
- Colitis microscopic (inflammation of colon with diarrhoea and abdominal cramps)
- Death
- Drug eruption (adverse drug reaction of the skin)
- Gastric cancer (stomach cancer)
- Interstitial lung disease
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
- Osteomyelitis (infection of bone)
What are the common drug interactions of Clopra and Cyramza, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Death
50-59:
- Colitis (inflammation of colon)
- Back pain
- Drug ineffective
- Flushing (the warm, red condition of human skin)
- Hyperhidrosis (abnormally increased sweating)
- Hypoxia (low oxygen in tissues)
- Malignant neoplasm progression (cancer tumour came back)
- Nausea (feeling of having an urge to vomit)
- Retching (strong involuntary effort to vomit)
60+:
- Pneumonia
- Febrile neutropenia (fever with reduced white blood cells)
- Colitis microscopic (inflammation of colon with diarrhoea and abdominal cramps)
- Drug eruption (adverse drug reaction of the skin)
- Gastric cancer (stomach cancer)
- Interstitial lung disease
- Decreased immune responsiveness
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
- Myelosuppression (a decrease in the production of blood cells)
- Osteomyelitis (infection of bone)
What are the existing conditions these people have? *
- Nausea (feeling of having an urge to vomit): 4 people, 26.67%
- Lung Neoplasm Malignant (cancer tumour of lung): 4 people, 26.67%
- Oesophageal Squamous Cell Carcinoma (cancer that begins in flat cells lining the oesophagus): 3 people, 20.00%
- Pneumonia: 3 people, 20.00%
- Gastric Cancer (stomach cancer): 3 people, 20.00%
- Diarrhea: 3 people, 20.00%
- Metastases To Bone (cancer spreads to bone): 3 people, 20.00%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 13.33%
- Constipation: 2 people, 13.33%
- Cancer Pain: 2 people, 13.33%
* Approximation only. Some reports may have incomplete information.
Do you take Clopra and Cyramza?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Clopra and Cyramza:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clopra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cyramza:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clopra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cyramza and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on metoclopramide hydrochloride and ramucirumab (the active ingredients of Clopra and Cyramza, respectively), and Clopra and Cyramza (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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