Clopra and Northera drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clopra (metoclopramide hydrochloride) and Northera (droxidopa). Common drug interactions include agitation among females and dysphagia among males.

The phase IV clinical study analyzes what interactions people have when they take Clopra and Northera. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Clopra?

Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.

What is Northera?

Northera has active ingredients of droxidopa. eHealthMe is studying from 22,874 Northera users. Check the latest studies of Northera.

On Jul, 31, 2026

11 people who take Clopra and Northera together, and have interactions are studied.

What are the common drug interactions of Clopra and Northera, by gender? *:

female:

Agitation (state of anxiety or nervous excitement)
Blood pressure fluctuation
Chills (felling of cold)
Contusion (a type of hematoma of tissue in which capillaries)
Hyperhidrosis (abnormally increased sweating)
Hypersensitivity
Muscle spasms (muscle contraction)
Palpitations (feelings or sensations that your heart is pounding or racing)
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Acute myocardial infarction (acute heart attack)

male:

Dysphagia (a condition in which swallowing is difficult or painful)
Aphasia (damage to the parts of the brain that control language)
Device occlusion
Embolic stroke (stroke due to obstruction due to an embolus)
Lung disorder (lung disease)
Pleural effusion (water on the lungs)
Dizziness
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Renal failure (kidney dysfunction)

What are the common drug interactions of Clopra and Northera, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Contusion (a type of hematoma of tissue in which capillaries)
Hypersensitivity

30-39:

Dizziness

40-49:

Agitation (state of anxiety or nervous excitement)

50-59:

n/a

60+:

Dysphagia (a condition in which swallowing is difficult or painful)
Aphasia (damage to the parts of the brain that control language)
Hyperhidrosis (abnormally increased sweating)
Muscle spasms (muscle contraction)
Device occlusion
Embolic stroke (stroke due to obstruction due to an embolus)
Lung disorder (lung disease)
Pleural effusion (water on the lungs)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 5 people, 45.45%
Migraine (headache): 2 people, 18.18%
Hypotension (abnormally low blood pressure): 2 people, 18.18%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 9.09%
Riley-Day Syndrome (abnormal functioning of the autonomic nervous system): 1 person, 9.09%
Parkinson's Disease: 1 person, 9.09%
Pain: 1 person, 9.09%
Nausea (feeling of having an urge to vomit): 1 person, 9.09%
Dizziness: 1 person, 9.09%
Coronary Artery Thrombosis (clot formation in coronary artery): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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