Clopra and Riboflavin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clopra (metoclopramide hydrochloride) and Riboflavin (riboflavin (vitamin b2)). Common drug interactions include refractory cancer among females and drug hypersensitivity among males.
The phase IV clinical study analyzes what interactions people have when they take Clopra and Riboflavin. It is created by eHealthMe based on reports of 92 people who take the same drugs from the FDA, and is updated regularly.
What is Clopra?
Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.
What is Riboflavin?
Riboflavin has active ingredients of riboflavin (vitamin b2). It is often used in migraine. eHealthMe is studying from 2,869 Riboflavin users. Check the latest studies of Riboflavin.
92 people who take Clopra and Riboflavin together, and have interactions are studied.

What are the common drug interactions of Clopra and Riboflavin, by gender? *:
female:
- Refractory cancer (cancer that has not responded to treatment)
- Skin discolouration (change of skin colour)
- Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
- Upper respiratory tract infection
- Abdominal pain
- Anaemia (lack of blood)
- Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
- Chest discomfort
- Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
- Colitis (inflammation of colon)
male:
- Drug hypersensitivity
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Colitis (inflammation of colon)
- Completed suicide (act of taking one's own life)
- Cytomegalovirus chorioretinitis (infection of choroid and retina of the eye from virus)
- Cytomegalovirus infection
- Decreased appetite
- Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
- Diarrhoea
- Ear infection viral
What are the common drug interactions of Clopra and Riboflavin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Upper respiratory tract infection
- Febrile neutropenia (fever with reduced white blood cells)
- Malignant neoplasm progression (cancer tumour came back)
- Refractory cancer (cancer that has not responded to treatment)
10-19:
- Burning sensation
- Erythema (redness of the skin)
- Pruritus (severe itching of the skin)
- Rash
- Nausea (feeling of having an urge to vomit)
- Bone tuberculosis
- Cardiac murmur (an heart sound in valve abnormality)
- Dizziness
- Fall
- Nasal discomfort
20-29:
n/a
30-39:
- Blood creatinine increased
- Cytomegalovirus chorioretinitis (infection of choroid and retina of the eye from virus)
- Depression
- Hepatitis a
- Hypertension (high blood pressure)
- Hypoaesthesia (reduced sense of touch or sensation)
- Pyelonephritis (inflammation of kidney caused by bacteria)
- Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
- Rhinitis allergic (inflammation of the nasal airways due to allergy)
- Vitreous floaters (spots before the eyes)
40-49:
- Chest pain
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Hypertension (high blood pressure)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Anxiety
- Palpitations (feelings or sensations that your heart is pounding or racing)
50-59:
- Drug hypersensitivity
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Pyrexia (fever)
- Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
- Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
- Anxiety
- Completed suicide (act of taking one's own life)
- Depression
60+:
- Vomiting
- Nausea (feeling of having an urge to vomit)
- Hepatitis acute
- Pleural effusion (water on the lungs)
- Pyrexia (fever)
- Abdominal pain
- Abdominal tenderness
- Anaemia (lack of blood)
- Bone pain
- Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
What are the existing conditions these people have? *
- Pneumonia: 52 people, 56.52%
- Ill-Defined Disorder: 47 people, 51.09%
- Erythema Multiforme (a type of hypersensitivity reaction): 47 people, 51.09%
- Diabetes: 40 people, 43.48%
- Immunodeficiency Common Variable: 10 people, 10.87%
- Nausea (feeling of having an urge to vomit): 7 people, 7.61%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 6.52%
- Depression: 5 people, 5.43%
* Approximation only. Some reports may have incomplete information.
Do you take Clopra and Riboflavin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Clopra (81,430 reports)
- Riboflavin (2,869 reports)
Browse all drug interactions of Clopra and Riboflavin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clopra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Riboflavin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clopra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Riboflavin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on metoclopramide hydrochloride and riboflavin (vitamin b2) (the active ingredients of Clopra and Riboflavin, respectively), and Clopra and Riboflavin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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