Clopra and Robitussin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clopra (metoclopramide hydrochloride) and Robitussin (guaifenesin). Common drug interactions include muscle contractions involuntary among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Clopra and Robitussin. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Clopra?

Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.

What is Robitussin?

Robitussin has active ingredients of guaifenesin. eHealthMe is studying from 3,532 Robitussin users. Check the latest studies of Robitussin.

On Aug, 04, 2026

71 people who take Clopra and Robitussin together, and have interactions are studied.

Clopra and Robitussin drug interactions.

What are the common drug interactions of Clopra and Robitussin, by gender? *:

female:

Muscle contractions involuntary (uncontrolled muscle contraction)
Myalgia (muscle pain)
Parathyroid disorder
Pneumonia
Postoperative wound infection
Sinus pain
Thyroid cancer recurrent (reoccurs thyroid cancer)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Ulcer
Abdominal discomfort

male:

Asthenia (weakness)
Chest discomfort
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Night sweats (sweating in night)
Productive cough
Pruritus (severe itching of the skin)
Pseudomonas test positive
Pyrexia (fever)
Secretion discharge
Sputum discoloured

What are the common drug interactions of Clopra and Robitussin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal mass (localized enlargement or swelling in the human abdomen)
Abdominal pain
Abdominal pain upper
Actinomycosis (infection that causes sores, or abscesses)
Albumin globulin ratio decreased
Alopecia (absence of hair from areas of the body)
Alveolitis (inflammation in the socket of a tooth)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Angina pectoris (chest pain due to ischemia of the heart muscle)

20-29:

Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Abdominal infection
Abdominal pain upper
Acidosis (build-up of carbon dioxide in the blood)
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Asthenia (weakness)
Back pain

30-39:

Asthenia (weakness)
Chest discomfort
Chest pain
Cough
Decreased appetite
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Headache (pain in head)
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)

40-49:

Chronic kidney disease
Headache (pain in head)
Influenza like illness
Renal failure (kidney dysfunction)
Dyspepsia (indigestion)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

50-59:

Thyroid cancer recurrent (reoccurs thyroid cancer)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Urinary tract infection
Abdominal discomfort
Acute respiratory distress syndrome
Anxiety
Apallic syndrome (serious brain damage, when cortical parts of the brain are disconnected from brainstem)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac disorder

60+:

Abdominal pain
Arthralgia (joint pain)
Productive cough
Pyrexia (fever)
Sinus congestion (blockage of sinus)
Pain
Renal failure (kidney dysfunction)
Chronic kidney disease
Vomiting
Wheezing (a high-pitched whistling sound made while you breath)

What are the existing conditions these people have? *

Pain: 19 people, 26.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 16 people, 22.54%
Nausea (feeling of having an urge to vomit): 15 people, 21.13%
Depression: 11 people, 15.49%
Cough: 10 people, 14.08%
Stress And Anxiety: 9 people, 12.68%
Immunodeficiency Common Variable: 9 people, 12.68%
Muscle Spasms (muscle contraction): 9 people, 12.68%
Wheezing (a high-pitched whistling sound made while you breath): 8 people, 11.27%
Constipation: 8 people, 11.27%

* Approximation only. Some reports may have incomplete information.

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