Co-codamol and Citalopram hydrobromide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Co-codamol (acetaminophen; codeine phosphate) and Citalopram hydrobromide (citalopram hydrobromide). Common drug interactions include haemoglobin decreased among females and metabolic acidosis among males.

The phase IV clinical study analyzes what interactions people have when they take Co-codamol and Citalopram hydrobromide. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Co-codamol?

Co-codamol has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 2,364 Co-codamol users. Check the latest studies of Co-codamol.

What is Citalopram hydrobromide?

Citalopram hydrobromide has active ingredients of citalopram hydrobromide. It is often used in depression. eHealthMe is studying from 36,878 Citalopram hydrobromide users. Check the latest studies of Citalopram hydrobromide.



On Jul, 17, 2026

17 people who take Co-codamol and Citalopram hydrobromide together, and have interactions are studied.

Co-codamol and Citalopram hydrobromide drug interactions.

What are the common drug interactions of Co-Codamol and Citalopram Hydrobromide, by gender? *:

female:

  1. Haemoglobin decreased
  2. Blood pressure decreased
  3. Dizziness
  4. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  5. Hypovolaemia (a decreased volume of circulating blood in the body)
  6. Pain in extremity
  7. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  8. Lacunar infarction (a type of stroke)
  9. Angle closure glaucoma (term used for several ocular diseases that ultimately result in increased intraocular pressure (iop) and decreased visual acuity)
  10. Asthenia (weakness)

male:

  1. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  2. Hypotension (abnormally low blood pressure)
  3. Suicide attempt
  4. Aggression
  5. Blood creatinine increased
  6. Blood lactic acid increased
  7. Blood potassium decreased
  8. Hypercalciuria (elevated calcium (ca+) level in the urine)
  9. Hyperoxaluria (excessive urinary excretion of oxalate)
  10. Lethargy (tiredness)

What are the common drug interactions of Co-Codamol and Citalopram Hydrobromide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  2. Hypotension (abnormally low blood pressure)
  3. Hypoxia (low oxygen in tissues)
  4. Loss of consciousness
  5. Chemical poisoning
  6. Crystalluria (crystals found in the urine)
  7. Heart rate increased
  8. Hypokalaemia (low potassium)
  9. Multiple drug overdose
  10. Suicide attempt

40-49:

  1. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  2. Lacunar infarction (a type of stroke)
  3. Asthenia (weakness)
  4. Bone pain
  5. Dyskinesia (abnormality or impairment of voluntary movement)
  6. Fatigue (feeling of tiredness)
  7. Pain in extremity

50-59:

  1. Nasal odour
  2. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)

60+:

  1. Haemoglobin decreased
  2. Blood pressure decreased
  3. Headache (pain in head)
  4. Hyperhidrosis (abnormally increased sweating)
  5. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  6. Hypotension (abnormally low blood pressure)
  7. Mood swings (an extreme or rapid change in mood)
  8. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  9. Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection)
  10. Pain in extremity

What are the existing conditions these people have? *

  1. Stress And Anxiety: 1 person, 5.88%
  2. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 5.88%
  3. Indigestion: 1 person, 5.88%
  4. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 5.88%
  5. Breast Cancer Metastatic: 1 person, 5.88%
  6. Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Co-codamol and Citalopram hydrobromide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Co-codamol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Citalopram hydrobromide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Co-codamol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Citalopram hydrobromide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate and citalopram hydrobromide (the active ingredients of Co-codamol and Citalopram hydrobromide, respectively), and Co-codamol and Citalopram hydrobromide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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