Coca and Lortab drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Coca (coca) and Lortab (acetaminophen; hydrocodone bitartrate). Common drug interactions include failure to thrive among females and acute respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Coca and Lortab. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Coca?

Coca has active ingredients of coca. eHealthMe is studying from 6,072 Coca users. Check the latest studies of Coca.

What is Lortab?

Lortab has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 31,285 Lortab users. Check the latest studies of Lortab.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

16 people who take Coca and Lortab together, and have interactions are studied.

What are the common drug interactions of Coca and Lortab, by gender? *:

female:

Failure to thrive (inadequate weight gain and physical growth in children)
Acetabulum fracture (socket of the hip joint- fracture)
Acute respiratory failure
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Confusional state
Drug ineffective
Fall
Haemorrhage intracranial (bleeding within the skull)
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Hypotension (abnormally low blood pressure)

male:

Acute respiratory failure
Haemorrhage intracranial (bleeding within the skull)
Streptococcal sepsis (whole body inflammation by streptococcal)
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Drug abuse
Drug diversion
Gallbladder non-functioning
Hepatorenal failure (decrease in kidney function in a person with a severe liver disorder)

What are the common drug interactions of Coca and Lortab, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Acute respiratory failure
Haemorrhage intracranial (bleeding within the skull)
Hypotension (abnormally low blood pressure)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Failure to thrive (inadequate weight gain and physical growth in children)
Pneumonia streptococcal (pneumonia, caused by streptococcus pneumoniae)
Sepsis (a severe blood infection that can lead to organ failure and death)
Adverse event
Overdose
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

20-29:

Lip swelling
Nasal oedema (fluid collection in nose)

30-39:

Abortion spontaneous (naturally occurring miscarriage)
Cardiac disorder
Craniosynostosis (a baby is born with an abnormally shaped skull or develops one during growth)
Developmental delay
Failure to thrive (inadequate weight gain and physical growth in children)
Gait disturbance
Jaundice neonatal (yellowing of skin in neonate)
Maternal exposure during pregnancy (use of substance during pregnancy)
Premature baby
Pyrexia (fever)

40-49:

Coma (state of unconsciousness lasting more than six hours)
Overdose
Unresponsive to stimuli
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)

50-59:

Acetabulum fracture (socket of the hip joint- fracture)
Acute respiratory failure
Internal injury
Lumbar vertebral fracture
Lung injury
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Pubic rami fracture
Rib fracture
Somnambulism (sleep walking)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

60+:

n/a

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 5 people, 31.25%
Depression: 5 people, 31.25%
Bone Pain: 4 people, 25.00%
Breast Cancer Metastatic: 4 people, 25.00%
Stress And Anxiety: 4 people, 25.00%
Dry Skin: 3 people, 18.75%
Breast Pain: 3 people, 18.75%
High Blood Pressure: 3 people, 18.75%
Hyperglycemia (high blood sugar): 3 people, 18.75%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 3 people, 18.75%

* Approximation only. Some reports may have incomplete information.

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