Rapamune and Ulcerative colitis - a phase IV clinical study of FDA data

Summary:

Ulcerative colitis is reported as a side effect among people who take Rapamune (sirolimus), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Lisinopril, and have Chronic respiratory failure.

The phase IV clinical study analyzes which people have Ulcerative colitis when taking Rapamune. It is created by eHealthMe based on reports of 13,732 people who have side effects when taking Rapamune from the FDA, and is updated regularly.

What is Rapamune?

Rapamune has active ingredients of sirolimus. It is often used in kidney transplant. eHealthMe is studying from 13,848 Rapamune users. Check the latest studies of Rapamune.

What is Ulcerative colitis?

Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine) is found to be associated with 1,195 drugs and 2,055 conditions by eHealthMe. Check the latest studies of Ulcerative colitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

13,732 people reported to have side effects when taking Rapamune.
Among them, 12 people (0.09%) have Ulcerative colitis.

Could Rapamune cause Ulcerative colitis?

Among these 12 people:

How long have people been on Rapamune when they have Ulcerative colitis? *

What is the gender of people who have Ulcerative colitis when taking Rapamune? *

female: 41.67 %
male: 58.33 %

What is the age of people who have Ulcerative colitis when taking Rapamune? *

What are other drugs people take besides Rapamune? *

Pravachol: 4 people, 33.33%
Lisinopril: 4 people, 33.33%
Trazodone Hydrochloride: 1 person, 8.33%
Protonix: 1 person, 8.33%
Prednisolone: 1 person, 8.33%
Pantoprazole Sodium: 1 person, 8.33%
Metoprolol Tartrate: 1 person, 8.33%
Fosamax: 1 person, 8.33%
Fluticasone Propionate: 1 person, 8.33%
Colchicine: 1 person, 8.33%

What are other side effects people have besides Ulcerative colitis? *

Kidney Infection (Pyelonephritis): 5 people, 41.67%
Irritable Bowel Syndrome: 4 people, 33.33%
The Flu (the flu is caused by an influenza virus): 3 people, 25.00%
Escherichia Urinary Tract Infection (urinary tract infection by escherichia coli): 2 people, 16.67%
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 2 people, 16.67%
General Physical Health Deterioration (weak health status): 2 people, 16.67%
Weight Decreased: 1 person, 8.33%
Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid): 1 person, 8.33%
Fever: 1 person, 8.33%
Drug Toxicity: 1 person, 8.33%

What are the existing conditions these people have? *

Lymphangioleiomyomatosis (a rare lung condition that affects a certain type of muscle cell and only occurs in women): 1 person, 8.33%
Chronic Respiratory Failure: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Rapamune and have Ulcerative colitis?

- Check whether Ulcerative colitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rapamune:

Rapamune (13,848 reports)

Browse all side effects of Rapamune:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ulcerative colitis:

Ulcerative colitis (1,195 drugs)

Browse all the conditions that are associated with Ulcerative colitis:

Ulcerative colitis (2,055 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on sirolimus (the active ingredients of Rapamune) and Rapamune (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.