Coca and Zyprexa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Coca (coca) and Zyprexa (olanzapine). Common drug interactions include overdose among females and weight increased among males.

The phase IV clinical study analyzes what interactions people have when they take Coca and Zyprexa. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Coca?

Coca has active ingredients of coca. eHealthMe is studying from 6,072 Coca users. Check the latest studies of Coca.

What is Zyprexa?

Zyprexa has active ingredients of olanzapine. It is often used in bipolar disorder. eHealthMe is studying from 64,724 Zyprexa users. Check the latest studies of Zyprexa.



On Jul, 25, 2026

42 people who take Coca and Zyprexa together, and have interactions are studied.

Coca and Zyprexa drug interactions.

What are the common drug interactions of Coca and Zyprexa, by gender? *:

female:

  1. Overdose
  2. Overweight
  3. Suicide attempt
  4. Cardiac failure congestive
  5. Diabetes mellitus inadequate control
  6. Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
  7. Multiple drug overdose intentional
  8. Obesity (having too much body fat)
  9. Pancreatitis (inflammation of pancreas)
  10. Self injurious behaviour

male:

  1. Weight increased
  2. Overdose
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  5. Diastolic dysfunction
  6. Haemoglobin decreased
  7. Hepatic lesion
  8. Pneumonia
  9. Respiratory failure (inadequate gas exchange by the respiratory system)
  10. Drug abuse

What are the common drug interactions of Coca and Zyprexa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Aggression
  2. Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
  3. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  4. Delusion (a false belief or opinion)
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  7. Hyperglycaemia (high blood sugar)
  8. Injury
  9. Insomnia (sleeplessness)
  10. Suicide attempt

30-39:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  3. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  4. Overweight
  5. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  6. Drug abuse
  7. Endocarditis (inflammation in heart muscle)
  8. Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
  9. Multiple drug overdose intentional
  10. Restless legs syndrome (a powerful urge to move your legs)

40-49:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Weight increased
  3. Overdose
  4. Blood urine present
  5. Chest pain
  6. Activated partial thromboplastin time prolonged
  7. Alanine aminotransferase increased
  8. Aspartate aminotransferase increased
  9. Cellulitis (infection under the skin)
  10. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

50-59:

  1. Bradypnoea (an abnormally slow respiratory rate)
  2. Depressed level of consciousness
  3. Hospitalisation
  4. Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
  5. Overdose
  6. Atrioventricular block (heart block)
  7. Lung disorder (lung disease)
  8. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  9. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
  10. Bradycardia (abnormally slow heart action)

60+:

  1. Aggression
  2. Agitation (state of anxiety or nervous excitement)
  3. Death
  4. Fall
  5. Head injury
  6. Incoherent (talking in a confused and unclear way)
  7. Loss of consciousness
  8. Pulmonary oedema (fluid accumulation in the lungs)
  9. Speech disorder

What are the existing conditions these people have? *

  1. Depression: 11 people, 26.19%
  2. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 7 people, 16.67%
  3. Stress And Anxiety: 4 people, 9.52%
  4. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 3 people, 7.14%
  5. Insomnia (sleeplessness): 3 people, 7.14%
  6. Drug Dependence: 3 people, 7.14%
  7. Alcoholism (problems with alcohol): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Coca and Zyprexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Coca:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zyprexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Coca and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zyprexa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on coca and olanzapine (the active ingredients of Coca and Zyprexa, respectively), and Coca and Zyprexa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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