Codeine sulfate and Prilosec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Codeine sulfate (codeine sulfate) and Prilosec (omeprazole). Common drug interactions include depression among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Codeine sulfate and Prilosec. It is created by eHealthMe based on reports of 89 people who take the same drugs from the FDA, and is updated regularly.

What is Codeine sulfate?

Codeine sulfate has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 4,510 Codeine sulfate users. Check the latest studies of Codeine sulfate.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,285 Prilosec users. Check the latest studies of Prilosec.

On Jul, 12, 2026

89 people who take Codeine sulfate and Prilosec together, and have interactions are studied.

Codeine sulfate and Prilosec drug interactions.

What are the common drug interactions of Codeine Sulfate and Prilosec, by gender? *:

female:

Depression
Diarrhoea
Injury
Chronic kidney disease
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Fatigue (feeling of tiredness)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Dysphagia (a condition in which swallowing is difficult or painful)
Exposed bone in jaw
Intervertebral disc protrusion (spinal disc protrusion)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Tremor (trembling or shaking movements in one or more parts of your body)
Weight increased
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Abdominal discomfort
Abdominal distension

What are the common drug interactions of Codeine Sulfate and Prilosec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Diarrhoea
Abdominal pain
Abdominal pain upper
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Contusion (a type of hematoma of tissue in which capillaries)
Depression
Dyspepsia (indigestion)
Eye swelling
Furuncle (infection of the hair follicle)
Hypertension (high blood pressure)

30-39:

Acute hepatic failure
Coagulation factor deficiency (lack of clotting substance in blood)
Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function)
Hepatorenal syndrome (renal failure in patients with advanced chronic liver disease)
Hyperglycaemia (high blood sugar)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Renal failure acute (rapid kidney dysfunction)

40-49:

Hot flush (sudden feelings of heat)
Hyperaesthesia
Hypercholesterolaemia (high levels of cholesterol in the blood)
Intervertebral disc protrusion (spinal disc protrusion)
Loose tooth
Lumbar spine flattening (flatten the curve of the lower spine)
Metastases to abdominal cavity (cancer spreads to abdominal cavity)
Metastases to bone (cancer spreads to bone)
Metastases to spine (cancer spreads to spine)
Mouth ulceration (mouth ulcers)

50-59:

Chronic kidney disease
Drug hypersensitivity
Renal failure (kidney dysfunction)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cerebrovascular disorder (disease of brain)
Renal tubular necrosis (death of kidney tubules)
Nephrogenic anaemia (anaemia due to kidney disease)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Death
Drug administration error

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Paralysis
Rash
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Asthenia (weakness)
Burning sensation
Chills (felling of cold)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

What are the existing conditions these people have? *

Depression: 12 people, 13.48%
High Blood Pressure: 11 people, 12.36%
Multiple Myeloma (cancer of the plasma cells): 8 people, 8.99%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 7 people, 7.87%
High Blood Cholesterol: 7 people, 7.87%
Cough: 7 people, 7.87%
Bone Loss: 7 people, 7.87%
Stress And Anxiety: 5 people, 5.62%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 5 people, 5.62%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 5.62%

* Approximation only. Some reports may have incomplete information.

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