Coenzyme q10 and Lortab drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Coenzyme q10 (coenzyme q - 10) and Lortab (acetaminophen; hydrocodone bitartrate). Common drug interactions include depression among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Coenzyme q10 and Lortab. It is created by eHealthMe based on reports of 99 people who take the same drugs from the FDA, and is updated regularly.

What is Coenzyme q10?

Coenzyme q10 has active ingredients of coenzyme q - 10. It is often used in high blood cholesterol. eHealthMe is studying from 23,438 Coenzyme q10 users. Check the latest studies of Coenzyme q10.

What is Lortab?

Lortab has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 31,285 Lortab users. Check the latest studies of Lortab.



On Jul, 19, 2026

99 people who take Coenzyme q10 and Lortab together, and have interactions are studied.

Coenzyme q10 and Lortab drug interactions.

What are the common drug interactions of Coenzyme Q10 and Lortab, by gender? *:

female:

  1. Depression
  2. Blood calcium decreased
  3. Blood magnesium decreased
  4. Blood potassium decreased
  5. Dizziness
  6. Drug ineffective
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  8. Heart rate increased
  9. Nephrolithiasis (calculi in the kidneys)
  10. Somnolence (a state of near-sleep, a strong desire for sleep)

male:

  1. Arthralgia (joint pain)
  2. Weight increased
  3. Iron deficiency anaemia
  4. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  5. Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
  6. Diarrhoea
  7. Confusional state
  8. Gastroduodenal haemorrhage (bleeding from stomach or duodenum ulcer)
  9. Rhinorrhoea (watery mucus discharge from the nose)
  10. Somnolence (a state of near-sleep, a strong desire for sleep)

What are the common drug interactions of Coenzyme Q10 and Lortab, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Constipation
  2. Vomiting

10-19:

n/a

20-29:

n/a

30-39:

  1. Accident
  2. C-reactive protein increased
  3. Confusional state
  4. Intervertebral disc protrusion (spinal disc protrusion)
  5. Pneumonia
  6. Somnolence (a state of near-sleep, a strong desire for sleep)
  7. Abdominal pain

40-49:

  1. Chronic kidney disease
  2. Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Anxiety
  5. Bone pain
  6. Drug resistance (reduction in effectiveness of a drug)
  7. Emotional distress
  8. Gait disturbance
  9. Renal impairment (severely reduced kidney function)
  10. Nausea (feeling of having an urge to vomit)

50-59:

  1. Dysphonia (speech disorder attributable to a disorder of phonation)
  2. Feeling hot
  3. Haemochromatosis (body to absorb more iron than usual from food)
  4. Hepatic steatosis (fatty liver disease)
  5. Hot flush (sudden feelings of heat)
  6. Hyperhidrosis (abnormally increased sweating)
  7. Insomnia (sleeplessness)
  8. Joint stiffness
  9. Muscle spasms (muscle contraction)
  10. Muscular weakness (muscle weakness)

60+:

  1. Arthralgia (joint pain)
  2. Rash
  3. Hypotension (abnormally low blood pressure)
  4. Intervertebral disc degeneration (spinal disc degeneration)
  5. Weight decreased
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Iron deficiency anaemia
  8. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  9. Pyrexia (fever)
  10. Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 19 people, 19.19%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 14 people, 14.14%
  3. Stress And Anxiety: 12 people, 12.12%
  4. Joint Pain: 12 people, 12.12%
  5. High Blood Pressure: 11 people, 11.11%
  6. Neck Pain: 10 people, 10.10%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 10.10%
  8. Nerve Compression: 9 people, 9.09%
  9. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 8 people, 8.08%
  10. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 8.08%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Coenzyme q10 and Lortab:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Coenzyme q10:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lortab:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Coenzyme q10 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lortab and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on coenzyme q - 10 and acetaminophen; hydrocodone bitartrate (the active ingredients of Coenzyme q10 and Lortab, respectively), and Coenzyme q10 and Lortab (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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