Cogentin and Avapro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cogentin (benztropine mesylate) and Avapro (irbesartan). Common drug interactions include anxiety among females and alanine aminotransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Cogentin and Avapro. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Cogentin?

Cogentin has active ingredients of benztropine mesylate. It is often used in tardive dyskinesia. eHealthMe is studying from 7,692 Cogentin users. Check the latest studies of Cogentin.

What is Avapro?

Avapro has active ingredients of irbesartan. It is often used in high blood pressure. eHealthMe is studying from 19,840 Avapro users. Check the latest studies of Avapro.

On Jul, 17, 2026

12 people who take Cogentin and Avapro together, and have interactions are studied.

What are the common drug interactions of Cogentin and Avapro, by gender? *:

female:

Anxiety
Depression
Device occlusion
Diabetes mellitus inadequate control
Diarrhoea
Dystonia (abnormal muscle tone)
Emotional disorder
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Mastoiditis (infection of mastoid bone)
Meningioma (a diverse set of tumours arising from the meninges)

male:

Alanine aminotransferase increased
Blood sodium increased
Exercise tolerance decreased
Globulins decreased
High density lipoprotein decreased
Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
Left ventricular dysfunction
Mitral valve incompetence (inefficient heart valve)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Supraventricular extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle)

What are the common drug interactions of Cogentin and Avapro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Granulocytopenia (lack of granulocyte)
Haematocrit decreased
Haemoglobin decreased
Red blood cell count decreased
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)

40-49:

Alanine aminotransferase increased
Blood cholesterol decreased
Diastolic dysfunction
Ejection fraction decreased (systolic heart failure)
Electrocardiogram pr prolongation
Exercise tolerance decreased
Globulins decreased
High density lipoprotein decreased
Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
Left ventricular dysfunction

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 25.00%
Bipolar Disorder (mood disorder): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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