Cogentin and Escitalopram drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cogentin (benztropine mesylate) and Escitalopram (escitalopram oxalate). Common drug interactions include rhabdomyolysis among females and speech disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Cogentin and Escitalopram. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Cogentin?

Cogentin has active ingredients of benztropine mesylate. It is often used in tardive dyskinesia. eHealthMe is studying from 7,692 Cogentin users. Check the latest studies of Cogentin.

What is Escitalopram?

Escitalopram has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 78,081 Escitalopram users. Check the latest studies of Escitalopram.

On Aug, 06, 2026

37 people who take Cogentin and Escitalopram together, and have interactions are studied.

Cogentin and Escitalopram drug interactions.

What are the common drug interactions of Cogentin and Escitalopram, by gender? *:

female:

Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Accommodation disorder
Diplopia (double vision)
Hypoaesthesia (reduced sense of touch or sensation)
Psychotic disorder
Strabismus (a disorder in which the two eyes do not line up in the same direction)
Visual acuity reduced (reduced clearness of vision)
Affect lability (emotional incontinence)
Alopecia (absence of hair from areas of the body)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

male:

Speech disorder
Dysphagia (a condition in which swallowing is difficult or painful)
Diarrhoea
Drooling (drop saliva uncontrollably from the mouth)
Dysstasia (difficulty in standing)
Emotional distress
Eye swelling
Fatigue (feeling of tiredness)
Hallucination (an experience involving the perception of something not present)
Hypertension (high blood pressure)

What are the common drug interactions of Cogentin and Escitalopram, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

20-29:

Accommodation disorder
Diplopia (double vision)
Strabismus (a disorder in which the two eyes do not line up in the same direction)
Visual acuity reduced (reduced clearness of vision)
Overdose
Pupillary reflex impaired
Weight increased

30-39:

Arrhythmia (irregular heartbeat)
Palpitations (feelings or sensations that your heart is pounding or racing)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

40-49:

Blood triglycerides increased
Death
Hypertension (high blood pressure)
Type 2 diabetes mellitus
Abdominal pain
Aggression
Agitation (state of anxiety or nervous excitement)
Arthralgia (joint pain)
Asthenia (weakness)
Back pain

50-59:

Physical disability
Pneumonia
Psychiatric symptom
Restless legs syndrome (a powerful urge to move your legs)
Road traffic accident
Salivary hypersecretion (excess saliva secretion)
Scab (a hard coating on the skin formed during the wound healing)
Scratch
Skin haemorrhage (bleeding into skin)
Somnolence (a state of near-sleep, a strong desire for sleep)

60+:

Gait disturbance
Speech disorder
Depressed level of consciousness
Drooling (drop saliva uncontrollably from the mouth)
Dysphonia (speech disorder attributable to a disorder of phonation)
Eye swelling
Hallucination (an experience involving the perception of something not present)
Hypersomnia (excessive daytime sleepiness (eds))
Oedema peripheral (superficial swelling)
Psychotic disorder

What are the existing conditions these people have? *

Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 14 people, 37.84%
Psychotic Disorder: 12 people, 32.43%
Encephalitis Autoimmune (autoimmune origin disturbances of consciousness and pyramidal signs, inflammation of the brain): 6 people, 16.22%
Parkinson's Disease: 4 people, 10.81%
Hallucinations (sensations that appear real but are created by your mind): 4 people, 10.81%
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 3 people, 8.11%
Stress And Anxiety: 2 people, 5.41%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 2 people, 5.41%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 2 people, 5.41%
Hypersensitivity: 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Cogentin and Escitalopram?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously