Colace and Trintellix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Colace (docusate ) and Trintellix (vortioxetine hydrobromide). Common drug interactions include lethargy among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Colace and Trintellix. It is created by eHealthMe based on reports of 96 people who take the same drugs from the FDA, and is updated regularly.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

What is Trintellix?

Trintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 13,067 Trintellix users. Check the latest studies of Trintellix.

On Jul, 13, 2026

96 people who take Colace and Trintellix together, and have interactions are studied.

Colace and Trintellix drug interactions.

What are the common drug interactions of Colace and Trintellix, by gender? *:

female:

Lethargy (tiredness)
Ligament sprain (ligament stretched)
Memory impairment
Migraine (headache)
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Oedema (fluid collection in tissue)
Pneumonia
Visual impairment
Weight increased
Blood pressure fluctuation

male:

Weight decreased
Abdominal discomfort
Fatigue (feeling of tiredness)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Hepatic mass
Hepatitis c
Hepatocellular carcinoma (liver cancer)
Hypertension (high blood pressure)
Hypotension (abnormally low blood pressure)
Infection

What are the common drug interactions of Colace and Trintellix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal distension
Anaemia (lack of blood)
Hospitalisation
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Somnolence (a state of near-sleep, a strong desire for sleep)
Suicidal ideation
Surgery

30-39:

n/a

40-49:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Ear infection
Hospitalisation
Poor quality sleep
Ill-defined disorder
Infusion related reaction
Diplopia (double vision)
Retinal vascular disorder (a range of eye diseases that affect the blood vessels in the eye)
Back pain
Cough

50-59:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Urticaria (rash of round, red welts on the skin that itch intensely)
Arthralgia (joint pain)
Cardiac arrest
Chest pain
Contusion (a type of hematoma of tissue in which capillaries)
Dehydration (dryness resulting from the removal of water)

60+:

Dysphagia (a condition in which swallowing is difficult or painful)
Acute myocardial infarction (acute heart attack)
Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
Nausea (feeling of having an urge to vomit)
Oedema (fluid collection in tissue)
Pneumonia
Visual impairment
Cataract (clouding of the lens inside the eye)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Disease recurrence

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 28 people, 29.17%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 17 people, 17.71%
Immunodeficiency Common Variable: 10 people, 10.42%
Pain: 7 people, 7.29%
Myeloid Leukaemia (a type of cancer in which the bone marrow makes abnormal myeloblasts): 7 people, 7.29%
High Blood Cholesterol: 7 people, 7.29%
Stress And Anxiety: 5 people, 5.21%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 5.21%
High Blood Pressure: 5 people, 5.21%
Asthma: 5 people, 5.21%

* Approximation only. Some reports may have incomplete information.

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