Paxil and Aphagia - a phase IV clinical study of FDA data

Summary:

Aphagia is reported as a side effect among people who take Paxil (paroxetine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Xanax, and have Bone neoplasm malignant.

The phase IV clinical study analyzes which people have Aphagia when taking Paxil. It is created by eHealthMe based on reports of 88,676 people who have side effects when taking Paxil from the FDA, and is updated regularly.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,546 Paxil users. Check the latest studies of Paxil.

What is Aphagia?

Aphagia (inability or refusal to swallow) is found to be associated with 541 drugs and 1,027 conditions by eHealthMe. Check the latest studies of Aphagia.



On Jul, 13, 2026

88,676 people reported to have side effects when taking Paxil.
Among them, 51 people (0.06%) have Aphagia.

Could Paxil cause Aphagia?

Among these 51 people:

How long have people been on Paxil when they have Aphagia? *

  • < 1 month: 83.33 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 16.67 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Aphagia when taking Paxil? *

  • female: 54.9 %
  • male: 45.1 %

What is the age of people who have Aphagia when taking Paxil? *

  • 0-1: 0.0 %
  • 2-9: 2.22 %
  • 10-19: 0.0 %
  • 20-29: 11.11 %
  • 30-39: 11.11 %
  • 40-49: 4.44 %
  • 50-59: 11.11 %
  • 60+: 60.0 %

What are other drugs people take besides Paxil? *

  1. Xanax: 12 people, 23.53%
  2. Aspirin: 10 people, 19.61%
  3. Zocor: 9 people, 17.65%
  4. Zantac: 9 people, 17.65%
  5. Prozac: 9 people, 17.65%
  6. Toprol-Xl: 9 people, 17.65%
  7. Lexapro: 9 people, 17.65%
  8. Valium: 8 people, 15.69%
  9. Lasix: 8 people, 15.69%
  10. Aredia: 8 people, 15.69%

What are other side effects people have besides Aphagia? *

  1. Nausea (feeling of having an urge to vomit): 21 people, 41.18%
  2. Weight Decreased: 18 people, 35.29%
  3. Nausea And Vomiting: 18 people, 35.29%
  4. Pain: 17 people, 33.33%
  5. Fatigue (feeling of tiredness): 16 people, 31.37%
  6. Dyspnea (difficult or laboured breathing): 16 people, 31.37%
  7. Back Pain: 16 people, 31.37%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 29.41%
  9. Insomnia (sleeplessness): 14 people, 27.45%
  10. Swallowing Difficulty: 13 people, 25.49%

What are the existing conditions these people have? *

  1. Bone Neoplasm Malignant (cancer of bone): 7 people, 13.73%
  2. Insomnia (sleeplessness): 5 people, 9.80%
  3. Pain: 4 people, 7.84%
  4. Breast Cancer: 4 people, 7.84%
  5. Nausea (feeling of having an urge to vomit): 3 people, 5.88%
  6. Hypersensitivity: 3 people, 5.88%
  7. Stable Angina (a constant chest pain): 3 people, 5.88%
  8. Birth Control: 3 people, 5.88%
  9. Headache (pain in head): 3 people, 5.88%
  10. Bipolar Disorder (mood disorder): 2 people, 3.92%

* Approximation only. Some reports may have incomplete information.

Do you take Paxil and have Aphagia?

- Check whether Aphagia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Paxil:

Aphagia treatments and more:

How severe was Aphagia and when was it recovered:

Expand to all the drugs that have ingredients of paroxetine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Paxil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aphagia:

Browse all the conditions that are associated with Aphagia:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on paroxetine hydrochloride (the active ingredients of Paxil) and Paxil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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