Colchicine and Advil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Colchicine (colchicine) and Advil (ibuprofen). Common drug interactions include rheumatoid arthritis among females and pain in extremity among males.

The phase IV clinical study analyzes what interactions people have when they take Colchicine and Advil. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.

What is Colchicine?

Colchicine has active ingredients of colchicine. It is often used in gout. eHealthMe is studying from 21,826 Colchicine users. Check the latest studies of Colchicine.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,533 Advil users. Check the latest studies of Advil.

On Jul, 07, 2026

78 people who take Colchicine and Advil together, and have interactions are studied.

What are the common drug interactions of Colchicine and Advil, by gender? *:

female:

Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Stress
Synovitis (inflammation of the synovial membrane)
Throat tightness
Ankylosing spondylitis (type of arthritis affecting the spine)
Drug hypersensitivity
Muscle spasms (muscle contraction)
Nodule (a growth of abnormal tissue)
Plantar fasciitis (painful inflammatory process of the plantar fascia)
Renal injury (kidney injury)

male:

Pain in extremity
Chronic kidney disease
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Muscle spasms (muscle contraction)
Oesophageal disorder (disease of oesophagus)
Rectal haemorrhage (bleeding from anus)
Respiration (transport of oxygen from the outside air to the cells within tissues)
Restlessness (not able to rest)
Fatigue (feeling of tiredness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

What are the common drug interactions of Colchicine and Advil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Acidosis (build-up of carbon dioxide in the blood)
Cardiac arrest
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypotension (abnormally low blood pressure)
Leukopenia (less number of white blood cells in blood)
Renal failure (kidney dysfunction)
Suicide attempt

20-29:

Attention deficit/hyperactivity disorder
Drug ineffective
Migraine (headache)

30-39:

Ankylosing spondylitis (type of arthritis affecting the spine)
Alanine aminotransferase increased
Arthralgia (joint pain)
Blood pressure increased
Chest pain
Fatigue (feeling of tiredness)
Heart valve incompetence (heart's valves do not work correctly)
Injury
Malaise (a feeling of general discomfort or uneasiness)
Muscular weakness (muscle weakness)

40-49:

Stress
Synovitis (inflammation of the synovial membrane)
Asthma
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Fibromyalgia (a long-term condition which causes pain all over the body)
Migraine (headache)
Multiple allergies (allergy to multiple agents)
Psoriasis (immune-mediated disease that affects the skin)
Alopecia (absence of hair from areas of the body)
Back pain

50-59:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Anal abscess
Impaired healing
Vertigo
Arthralgia (joint pain)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Fatigue (feeling of tiredness)
Hyperhidrosis (abnormally increased sweating)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Dysphagia (a condition in which swallowing is difficult or painful)
Energy increased
Feeling hot
Gait disturbance
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hyperglycaemia (high blood sugar)
Hypoaesthesia (reduced sense of touch or sensation)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 17.95%
Multiple Myeloma (cancer of the plasma cells): 10 people, 12.82%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 10.26%
High Blood Cholesterol: 8 people, 10.26%
High Blood Pressure: 6 people, 7.69%
Primary Myelofibrosis (primary disorder of the bone marrow): 5 people, 6.41%
Malignant Melanoma (skin cancer rises from melancytes): 5 people, 6.41%
Headache (pain in head): 5 people, 6.41%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 5.13%
Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 4 people, 5.13%

* Approximation only. Some reports may have incomplete information.

Do you take Colchicine and Advil?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously