Colchicine and Indocin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Colchicine (colchicine) and Indocin (indomethacin). Common drug interactions include anxiety among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Colchicine and Indocin. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Colchicine?

Colchicine has active ingredients of colchicine. It is often used in gout. eHealthMe is studying from 21,826 Colchicine users. Check the latest studies of Colchicine.

What is Indocin?

Indocin has active ingredients of indomethacin. It is often used in gout. eHealthMe is studying from 4,559 Indocin users. Check the latest studies of Indocin.

On Jul, 08, 2026

69 people who take Colchicine and Indocin together, and have interactions are studied.

Colchicine and Indocin drug interactions.

What are the common drug interactions of Colchicine and Indocin, by gender? *:

female:

Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic dilatation
Arrhythmia (irregular heartbeat)
Arthralgia (joint pain)
Asthma
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrophic vulvovaginitis (inflammation of the vulva)
Bone disorder
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)

male:

Renal failure (kidney dysfunction)
Chronic kidney disease
Gait disturbance
Neuropathy peripheral (surface nerve damage)
Abdominal pain upper
Anaemia (lack of blood)
Arthralgia (joint pain)
Asthenia (weakness)
Death
Dehydration (dryness resulting from the removal of water)

What are the common drug interactions of Colchicine and Indocin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)
Anxiety
Asthma
Bone disorder
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bone pain
Decreased appetite
Decreased interest
Dizziness

40-49:

Abdominal pain upper
Anger
Cardiac failure congestive
Cardiomyopathy (weakening of the heart muscle)
Cardiovascular disorder (heart diseases)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Emotional disorder
Hypercholesterolaemia (high levels of cholesterol in the blood)
Hypertension (high blood pressure)
Liver injury

50-59:

Renal failure acute (rapid kidney dysfunction)
Therapeutic response decreased (less preventive response)
Thrombosis (formation of a blood clot inside a blood vessel)
Chronic kidney disease
Renal failure (kidney dysfunction)
Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
Hypovolaemic shock (shock caused by severe blood or fluid loss)
Weight increased
Nephrogenic anaemia (anaemia due to kidney disease)
Arthralgia (joint pain)

60+:

Drug hypersensitivity
Cholecystitis infective (infection of gallbladder capable to infect other organs)
Activities of daily living impaired
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Axonal neuropathy (dysfunction of axon nerves)
Burning sensation
Contusion (a type of hematoma of tissue in which capillaries)
Death

What are the existing conditions these people have? *

Pain: 17 people, 24.64%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 15 people, 21.74%
High Blood Pressure: 15 people, 21.74%
High Blood Cholesterol: 13 people, 18.84%
Diabetes: 12 people, 17.39%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 15.94%
Autonomic Neuropathy (malfunction of the autonomic nervous system (ans)): 6 people, 8.70%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 6 people, 8.70%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 6 people, 8.70%
Prostatomegaly (enlargement of the prostate): 6 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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