Colcrys and Seroquel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Colcrys (colchicine) and Seroquel (quetiapine fumarate). Common drug interactions include therapeutic response unexpected among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Colcrys and Seroquel. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Colcrys?

Colcrys has active ingredients of colchicine. It is often used in gout. eHealthMe is studying from 4,546 Colcrys users. Check the latest studies of Colcrys.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.



On Jul, 27, 2026

44 people who take Colcrys and Seroquel together, and have interactions are studied.

Colcrys and Seroquel drug interactions.

What are the common drug interactions of Colcrys and Seroquel, by gender? *:

female:

  1. Therapeutic response unexpected
  2. Urinary tract infection
  3. Vomiting
  4. Fatigue (feeling of tiredness)
  5. Blood cholesterol increased
  6. Cardiac murmur (an heart sound in valve abnormality)
  7. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  8. Endometrial cancer
  9. Hepatic failure (liver failure)
  10. Hypertension (high blood pressure)

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Application site pain
  4. Wound complication
  5. Cardiac disorder
  6. Dehydration (dryness resulting from the removal of water)
  7. Fatigue (feeling of tiredness)
  8. Headache (pain in head)
  9. Hypotension (abnormally low blood pressure)
  10. Memory impairment

What are the common drug interactions of Colcrys and Seroquel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Application site pain
  5. Wound complication
  6. Blood potassium decreased
  7. Confusional state
  8. Lethargy (tiredness)
  9. Periarthritis (inflammation of the external coats of an artery and of the tissues around the artery)
  10. Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Anxiety
  4. Affective disorder (mental disorder)
  5. Asthenia (weakness)
  6. Dyspnoea (difficult or laboured respiration)
  7. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  8. Muscle spasms (muscle contraction)
  9. Nephrogenic anaemia (anaemia due to kidney disease)
  10. Post-traumatic stress disorder

60+:

  1. Blood cholesterol increased
  2. Cardiac murmur (an heart sound in valve abnormality)
  3. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  4. Ovarian cancer (cancer of ovary)
  5. Psychomotor hyperactivity (feelings of extreme restlessness)
  6. Renal failure chronic (long lasting kidney dysfunction)
  7. Thyroid disorder (thyroid diseases)
  8. Adverse drug reaction
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Haematochezia (passage of stools containing blood)

What are the existing conditions these people have? *

  1. High Blood Pressure: 21 people, 47.73%
  2. Pain: 19 people, 43.18%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 17 people, 38.64%
  4. High Blood Cholesterol: 16 people, 36.36%
  5. Depression: 14 people, 31.82%
  6. Diabetes: 12 people, 27.27%
  7. Infection: 12 people, 27.27%
  8. Stress And Anxiety: 11 people, 25.00%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 10 people, 22.73%
  10. Oedema (fluid collection in tissue): 9 people, 20.45%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Colcrys and Seroquel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Colcrys:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Seroquel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Colcrys and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Seroquel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on colchicine and quetiapine fumarate (the active ingredients of Colcrys and Seroquel, respectively), and Colcrys and Seroquel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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