Colcrys and Trulicity drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Colcrys (colchicine) and Trulicity (dulaglutide). Common drug interactions include anxiety among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Colcrys and Trulicity. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Colcrys?

Colcrys has active ingredients of colchicine. It is often used in gout. eHealthMe is studying from 4,546 Colcrys users. Check the latest studies of Colcrys.

What is Trulicity?

Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.



On Aug, 12, 2026

33 people who take Colcrys and Trulicity together, and have interactions are studied.

Colcrys and Trulicity drug interactions.

What are the common drug interactions of Colcrys and Trulicity, by gender? *:

female:

  1. Anxiety
  2. Blood pressure increased
  3. Burning sensation
  4. Hyperventilation
  5. Urticaria (rash of round, red welts on the skin that itch intensely)
  6. Blood glucose increased
  7. Chronic kidney disease
  8. Fatigue (feeling of tiredness)
  9. Headache (pain in head)
  10. Joint swelling

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Injection site erythema (redness at injection site)
  5. Injection site swelling
  6. Migraine (headache)
  7. Neck pain
  8. Pain
  9. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  10. Post procedural swelling

What are the common drug interactions of Colcrys and Trulicity, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Eosinophilia (eosinophil count in the peripheral blood exceeds)
  2. Liver disorder (liver diseases)
  3. Lymphadenopathy (disease or enlargement of lymph nodes)
  4. Rash

50-59:

  1. Chronic kidney disease
  2. Abdominal pain
  3. Diarrhoea
  4. Abscess (pus)
  5. Abscess neck (neck abscesses)
  6. Anal abscess
  7. Cellulitis (infection under the skin)
  8. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  9. Genital abscess (build up of pus in genital)
  10. Groin abscess (pus in groin)

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  4. Hyperventilation
  5. Injection site erythema (redness at injection site)
  6. Injection site swelling
  7. Post procedural swelling
  8. Renal injury (kidney injury)
  9. Urticaria (rash of round, red welts on the skin that itch intensely)
  10. Blood glucose increased

What are the existing conditions these people have? *

  1. Diabetes: 16 people, 48.48%
  2. High Blood Pressure: 14 people, 42.42%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 42.42%
  4. High Blood Cholesterol: 14 people, 42.42%
  5. Type 2 Diabetes: 11 people, 33.33%
  6. Cardiac Disorder: 11 people, 33.33%
  7. Pain: 9 people, 27.27%
  8. Indigestion: 8 people, 24.24%
  9. Infection: 7 people, 21.21%
  10. Inflammation: 7 people, 21.21%

* Approximation only. Some reports may have incomplete information.

Do you take Colcrys and Trulicity?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Colcrys and Trulicity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Colcrys:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Trulicity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Colcrys and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Trulicity and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on colchicine and dulaglutide (the active ingredients of Colcrys and Trulicity, respectively), and Colcrys and Trulicity (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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