Colecalciferol and Evenity drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Colecalciferol (cholecalciferol) and Evenity (romosozumab-aqqg). Common drug interactions include headache among females and cardiac failure among males.

The phase IV clinical study analyzes what interactions people have when they take Colecalciferol and Evenity. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Colecalciferol?

Colecalciferol has active ingredients of cholecalciferol. eHealthMe is studying from 21,262 Colecalciferol users. Check the latest studies of Colecalciferol.

What is Evenity?

Evenity has active ingredients of romosozumab-aqqg. eHealthMe is studying from 9,485 Evenity users. Check the latest studies of Evenity.



On Jul, 12, 2026

40 people who take Colecalciferol and Evenity together, and have interactions are studied.

Colecalciferol and Evenity drug interactions.

What are the common drug interactions of Colecalciferol and Evenity, by gender? *:

female:

  1. Headache (pain in head)
  2. Injection site erythema (redness at injection site)
  3. Injection site pain
  4. Arthralgia (joint pain)
  5. Bone pain
  6. Fall
  7. Osteonecrosis of jaw (death of bone of jaw)
  8. Weight increased
  9. Cellulitis (infection under the skin)
  10. Groin pain

male:

  1. Cardiac failure
  2. Cardiac failure congestive
  3. Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
  4. Decreased appetite
  5. Osteonecrosis of jaw (death of bone of jaw)
  6. Pneumonia
  7. Post procedural myocardial infarction (post procedural heart attack)
  8. Tooth extraction

What are the common drug interactions of Colecalciferol and Evenity, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Bladder dilatation
  2. Headache (pain in head)
  3. Injection site swelling
  4. Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
  5. Multiple fractures
  6. Osteoporosis (bones weak and more likely to break)
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  8. Shunt occlusion (blockage of shunt)
  9. Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)

50-59:

n/a

60+:

  1. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  2. Osteonecrosis of jaw (death of bone of jaw)
  3. Injection site swelling
  4. Back pain
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  6. Bone disorder
  7. Exostosis (formation of new bone on the surface of a bone)
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Impaired healing
  10. Insomnia (sleeplessness)

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 22 people, 55.00%
  2. Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 17 people, 42.50%
  3. High Blood Pressure: 6 people, 15.00%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 7.50%
  5. Renal Disorder (kidney disease): 2 people, 5.00%
  6. Polymyalgia Rheumatica (pain in many muscles): 2 people, 5.00%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.00%
  8. Dyslipidaemia (abnormal amount of lipids): 2 people, 5.00%
  9. Back Pain: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Colecalciferol and Evenity?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Colecalciferol and Evenity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Colecalciferol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Evenity:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Colecalciferol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Evenity and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cholecalciferol and romosozumab-aqqg (the active ingredients of Colecalciferol and Evenity, respectively), and Colecalciferol and Evenity (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: