Colestid and Pentasa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Colestid (colestipol hydrochloride) and Pentasa (mesalamine). Common drug interactions include aneurysm among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Colestid and Pentasa. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Colestid?

Colestid has active ingredients of colestipol hydrochloride. It is often used in irritable bowel syndrome. eHealthMe is studying from 2,233 Colestid users. Check the latest studies of Colestid.

What is Pentasa?

Pentasa has active ingredients of mesalamine. It is often used in crohn's disease. eHealthMe is studying from 23,325 Pentasa users. Check the latest studies of Pentasa.



On Jul, 26, 2026

59 people who take Colestid and Pentasa together, and have interactions are studied.

Colestid and Pentasa drug interactions.

What are the common drug interactions of Colestid and Pentasa, by gender? *:

female:

  1. Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
  2. Chest discomfort
  3. Blood pressure decreased
  4. Presyncope
  5. Pulse absent
  6. Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
  7. Troponin increased
  8. Blood pressure increased
  9. Fall
  10. Upper limb fracture

male:

  1. Pneumonia
  2. Lymphadenitis (inflammation or enlargement of a lymph node)
  3. Abdominal pain lower
  4. Abscess (pus)
  5. Anxiety
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  7. Asthenia (weakness)
  8. Back pain
  9. Benign prostatic hyperplasia (benign enlargement of the prostate)
  10. Bladder trabeculation (bladder trabeculation is characterized by a thick wall and hypertrophied muscle bundles)

What are the common drug interactions of Colestid and Pentasa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Emotional distress
  3. Inflammatory bowel disease
  4. Intestinal obstruction
  5. Liver abscess (pus in liver)
  6. Nausea (feeling of having an urge to vomit)
  7. Vomiting

30-39:

  1. Injection site swelling
  2. Pain
  3. Sensation of heaviness
  4. Weight increased
  5. Abdominal pain
  6. Abdominal pain lower
  7. Abscess (pus)
  8. Anxiety
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  10. Benign prostatic hyperplasia (benign enlargement of the prostate)

40-49:

  1. Chest discomfort
  2. Craniocerebral injury (injury to cranium and brain)
  3. Dyspepsia (indigestion)
  4. Dysphagia (a condition in which swallowing is difficult or painful)
  5. Lip pain
  6. Rash pruritic (redness with itching)
  7. Swelling
  8. Syncope (loss of consciousness with an inability to maintain postural tone)
  9. Lymphadenitis (inflammation or enlargement of a lymph node)
  10. Abdominal discomfort

50-59:

  1. Cough
  2. Migraine (headache)
  3. Heart rate decreased
  4. Nausea (feeling of having an urge to vomit)
  5. Pneumonia
  6. Abdominal discomfort
  7. Alanine aminotransferase increased
  8. Alopecia (absence of hair from areas of the body)
  9. Anorectal discomfort
  10. Anxiety

60+:

  1. Acidosis (build-up of carbon dioxide in the blood)
  2. Cardiac failure congestive
  3. Joint swelling
  4. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  5. Therapeutic response decreased (less preventive response)
  6. Vision blurred
  7. Dyspnoea (difficult or laboured respiration)
  8. Hypokalaemia (low potassium)
  9. Hypoxia (low oxygen in tissues)
  10. Influenza

What are the existing conditions these people have? *

  1. Pain: 14 people, 23.73%
  2. Diarrhea: 6 people, 10.17%
  3. Rickets (softening of bones): 4 people, 6.78%
  4. Iron Deficiency Anaemia: 4 people, 6.78%
  5. Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 5.08%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Colestid and Pentasa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Colestid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Pentasa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Colestid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pentasa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on colestipol hydrochloride and mesalamine (the active ingredients of Colestid and Pentasa, respectively), and Colestid and Pentasa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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