Desyrel and Tooth fracture - a phase IV clinical study of FDA data

Summary:

Tooth fracture is reported as a side effect among people who take Desyrel (trazodone hydrochloride), especially for people who are female, 50-59 old, also take Zometa, and have Metastases to bone.

The phase IV clinical study analyzes which people have Tooth fracture when taking Desyrel. It is created by eHealthMe based on reports of 6,042 people who have side effects when taking Desyrel from the FDA, and is updated regularly.

What is Desyrel?

Desyrel has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 6,595 Desyrel users. Check the latest studies of Desyrel.

What is Tooth fracture?

Tooth fracture is found to be associated with 1,034 drugs and 900 conditions by eHealthMe. Check the latest studies of Tooth fracture.

On Jul, 26, 2026

6,042 people reported to have side effects when taking Desyrel.
Among them, 50 people (0.83%) have Tooth fracture.

$Could Desyrel cause Tooth fracture?$

Among these 50 people:

What is the gender of people who have Tooth fracture when taking Desyrel? *

female: 81.25 %
male: 18.75 %

What is the age of people who have Tooth fracture when taking Desyrel? *

What are other drugs people take besides Desyrel? *

What are other side effects people have besides Tooth fracture? *

Pain: 43 people, 86.00%
Stress And Anxiety: 40 people, 80.00%
Spinal Osteoarthritis (joint cartilage loss in spine): 39 people, 78.00%
Anhedonia (inability to experience pleasure from activities usually found enjoyable): 36 people, 72.00%
Toothaches (tooth pain): 33 people, 66.00%
Osteonecrosis Of Jaw (death of bone of jaw): 32 people, 64.00%
Pain In Extremity: 32 people, 64.00%
Gait Disturbance: 32 people, 64.00%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 31 people, 62.00%
Atelectasis (partial or complete collapse of the lung): 31 people, 62.00%

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 15 people, 30.00%
Bone Density Abnormal: 14 people, 28.00%
Bone Pain: 13 people, 26.00%
Breast Cancer: 13 people, 26.00%
Stress And Anxiety: 13 people, 26.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 26.00%
Breast Cancer Metastatic: 6 people, 12.00%
Bone Density Decreased: 5 people, 10.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 10.00%
Osteoporosis (bones weak and more likely to break): 5 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Desyrel and have Tooth fracture?

- Check whether Tooth fracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Desyrel:

Desyrel (6,595 reports)

Tooth fracture treatments and more:

Tooth fracture (15,314 reports)

Browse all side effects of Desyrel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tooth fracture:

Tooth fracture (1,034 drugs)

Browse all the conditions that are associated with Tooth fracture:

Tooth fracture (900 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on trazodone hydrochloride (the active ingredients of Desyrel) and Desyrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.