Combipatch and Alendronate sodium drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Combipatch (estradiol; norethindrone acetate) and Alendronate sodium (alendronate sodium). Common drug interactions include abdominal discomfort among females.
The phase IV clinical study analyzes what interactions people have when they take Combipatch and Alendronate sodium. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Combipatch?
Combipatch has active ingredients of estradiol; norethindrone acetate. It is often used in menopause. eHealthMe is studying from 3,599 Combipatch users. Check the latest studies of Combipatch.
What is Alendronate sodium?
Alendronate sodium has active ingredients of alendronate sodium. It is often used in osteoporosis. eHealthMe is studying from 43,608 Alendronate sodium users. Check the latest studies of Alendronate sodium.
14 people who take Combipatch and Alendronate sodium together, and have interactions are studied.
What are the common drug interactions of Combipatch and Alendronate Sodium, by gender? *:
female:
- Abdominal discomfort
- Adverse event
- Medical device complication
- Muscle strain (an injury to a muscle in which the muscle fibres tear)
- Muscular weakness (muscle weakness)
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Pain in extremity
- Skin reaction
- Vitamin d deficiency
- Skull fracture
male:
n/a
What are the common drug interactions of Combipatch and Alendronate Sodium, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Abdominal discomfort
- Adverse event
- Medical device complication
- Muscle strain (an injury to a muscle in which the muscle fibres tear)
- Muscular weakness (muscle weakness)
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Pain in extremity
- Skin reaction
- Vitamin d deficiency
- Skull fracture
60+:
n/a
What are the existing conditions these people have? *
- Osteopenia (a condition where bone mineral density is lower than normal): 9 people, 64.29%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 28.57%
- Stress And Anxiety: 2 people, 14.29%
- Depression: 2 people, 14.29%
- High Blood Cholesterol: 2 people, 14.29%
- Hot Flush (sudden feelings of heat): 2 people, 14.29%
- Ill-Defined Disorder: 2 people, 14.29%
- Immunodeficiency Disorders: 2 people, 14.29%
- Oedema Peripheral (superficial swelling): 2 people, 14.29%
- Insomnia (sleeplessness): 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Combipatch and Alendronate sodium?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Combipatch (3,599 reports)
- Alendronate sodium (43,608 reports)
Browse all drug interactions of Combipatch and Alendronate sodium:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Combipatch:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Alendronate sodium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Combipatch and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Alendronate sodium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Stuckey BG, Sallie R, "Alendronate-induced unmasking or deterioration of coeliac disease: a case series", Osteoporosis International, 2015 Jan .
- Lee WY, Sun LM, Lin MC, Liang JA, Chang SN, Sung FC, Muo CH, Kao CH, "A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study", PloS one, 2012 Dec .
- Stuckey BG, Sallie R, "Alendronate-induced unmasking or deterioration of coeliac disease: a case series", Osteoporosis International, 2015 Jan .
- Lee WY, Sun LM, Lin MC, Liang JA, Chang SN, Sung FC, Muo CH, Kao CH, "A higher dosage of oral alendronate will increase the subsequent cancer risk of osteoporosis patients in Taiwan: a population-based cohort study", PloS one, 2012 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on estradiol; norethindrone acetate and alendronate sodium (the active ingredients of Combipatch and Alendronate sodium, respectively), and Combipatch and Alendronate sodium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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