Combipatch and Luvox drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Combipatch (estradiol; norethindrone acetate) and Luvox (fluvoxamine maleate). Common drug interactions include blood cholesterol increased among females.
The phase IV clinical study analyzes what interactions people have when they take Combipatch and Luvox. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Combipatch?
Combipatch has active ingredients of estradiol; norethindrone acetate. It is often used in menopause. eHealthMe is studying from 3,599 Combipatch users. Check the latest studies of Combipatch.
What is Luvox?
Luvox has active ingredients of fluvoxamine maleate. It is often used in obsessive-compulsive disorder. eHealthMe is studying from 13,440 Luvox users. Check the latest studies of Luvox.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
11 people who take Combipatch and Luvox together, and have interactions are studied.

What are the common drug interactions of Combipatch and Luvox, by gender? *:
female:
- Blood cholesterol increased
- Breast cancer
- Alanine aminotransferase increased
- Anaemia (lack of blood)
- Aspartate aminotransferase increased
- Atelectasis (partial or complete collapse of the lung)
- Atrophic vulvovaginitis (inflammation of the vulva)
- Bilirubin conjugated increased
- Blood alkaline phosphatase increased
- Blood bilirubin increased
male:
n/a
What are the common drug interactions of Combipatch and Luvox, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Haematemesis (vomiting of blood)
- Nausea (feeling of having an urge to vomit)
- Vomiting
50-59:
- Blood cholesterol increased
- Breast cancer
- Aspartate aminotransferase increased
- Atelectasis (partial or complete collapse of the lung)
- Atrophic vulvovaginitis (inflammation of the vulva)
- Bilirubin conjugated increased
- Blood alkaline phosphatase increased
- Blood bilirubin increased
- Blood pressure increased
- Blood triglycerides increased
60+:
n/a
What are the existing conditions these people have? *
- Depression: 11 people, 100.00%
- Sleep Disorder: 6 people, 54.55%
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 1 person, 9.09%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 9.09%
- Menopausal Symptoms: 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Combipatch and Luvox?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Combipatch (3,599 reports)
- Luvox (13,440 reports)
Browse all drug interactions of Combipatch and Luvox:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Combipatch:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Luvox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Combipatch and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Luvox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .
- Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on estradiol; norethindrone acetate and fluvoxamine maleate (the active ingredients of Combipatch and Luvox, respectively), and Combipatch and Luvox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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