Combivent respimat and Zoloft drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Combivent respimat (albuterol sulfate; ipratropium bromide) and Zoloft (sertraline hydrochloride). Common drug interactions include lower respiratory tract infection bacterial among females and basal cell carcinoma among males.

The phase IV clinical study analyzes what interactions people have when they take Combivent respimat and Zoloft. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.

What is Combivent respimat?

Combivent respimat has active ingredients of albuterol sulfate; ipratropium bromide. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 2,696 Combivent respimat users. Check the latest studies of Combivent respimat.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.



On Jul, 18, 2026

70 people who take Combivent respimat and Zoloft together, and have interactions are studied.

Combivent respimat and Zoloft drug interactions.

What are the common drug interactions of Combivent Respimat and Zoloft, by gender? *:

female:

  1. Lower respiratory tract infection bacterial
  2. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  3. Pain
  4. Peripheral swelling
  5. Plasma cell myeloma (cancer that begins in plasma cells)
  6. Pleural effusion (water on the lungs)
  7. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  8. Respiratory tract infection
  9. Scoliosis (a medical condition in which a person's spine is curved from side to side)
  10. Sepsis (a severe blood infection that can lead to organ failure and death)

male:

  1. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  2. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  3. Weight decreased
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  5. Pulmonary mass
  6. Subcutaneous abscess
  7. Aphasia (damage to the parts of the brain that control language)
  8. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  9. Confusional state
  10. Delirium (wild excitement)

What are the common drug interactions of Combivent Respimat and Zoloft, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Upper respiratory tract infection

50-59:

  1. Blood potassium decreased
  2. Cardiac disorder
  3. Drug ineffective
  4. Fluid retention (an abnormal accumulation of fluid in the blood)
  5. Food intolerance (inability to have food)
  6. Gout (uric acid crystals building up in the body)
  7. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  8. Loss of consciousness
  9. Peripheral swelling
  10. Suicidal ideation

60+:

  1. Sinusitis (inflammation of sinus)
  2. Localised infection (infection at the single location)
  3. Headache (pain in head)
  4. Infection
  5. Insomnia (sleeplessness)
  6. Nephropathy (damage to or disease of a kidney)
  7. Renal failure (kidney dysfunction)
  8. Respiratory tract infection
  9. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  10. Pulmonary mass

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 20 people, 28.57%
  2. Stable Angina (a constant chest pain): 8 people, 11.43%
  3. Pain: 8 people, 11.43%
  4. Nausea (feeling of having an urge to vomit): 8 people, 11.43%
  5. Hypersensitivity: 6 people, 8.57%
  6. Asthma: 6 people, 8.57%
  7. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 7.14%
  8. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 5 people, 7.14%
  9. Nasal Dryness (dry nose): 5 people, 7.14%
  10. Insomnia (sleeplessness): 5 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Combivent respimat and Zoloft:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Combivent respimat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zoloft:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Combivent respimat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zoloft and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on albuterol sulfate; ipratropium bromide and sertraline hydrochloride (the active ingredients of Combivent respimat and Zoloft, respectively), and Combivent respimat and Zoloft (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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