Combivent and Lotensin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Combivent (albuterol sulfate; ipratropium bromide) and Lotensin (benazepril hydrochloride). Common drug interactions include pain among females and weight decreased among males.
The phase IV clinical study analyzes what interactions people have when they take Combivent and Lotensin. It is created by eHealthMe based on reports of 98 people who take the same drugs from the FDA, and is updated regularly.
What is Combivent?
Combivent has active ingredients of albuterol sulfate; ipratropium bromide. It is often used in asthma. eHealthMe is studying from 35,341 Combivent users. Check the latest studies of Combivent.
What is Lotensin?
Lotensin has active ingredients of benazepril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 8,037 Lotensin users. Check the latest studies of Lotensin.
98 people who take Combivent and Lotensin together, and have interactions are studied.

What are the common drug interactions of Combivent and Lotensin, by gender? *:
female:
- Pain
- Pain in extremity
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Weight increased
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Chest pain
- Diarrhoea
- Back pain
- Depression
male:
- Weight decreased
- Cardiac failure congestive
- Pneumonia streptococcal (pneumonia, caused by streptococcus pneumoniae)
- Renal failure chronic (long lasting kidney dysfunction)
- Injury
- Pain
- Vomiting
- Anaemia of chronic disease
- Cough
- Drug ineffective
What are the common drug interactions of Combivent and Lotensin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Activities of daily living impaired
- Arthralgia (joint pain)
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Comminuted fracture (bone has broken into several pieces)
- Cystitis interstitial (unknown cause characterized by bladder pain)
- Fall
- Femur fracture
- Haemoglobin decreased
- Mobility decreased (ability to move is reduced)
- Nervous system disorder (a general class of medical conditions affecting the nervous system)
30-39:
- Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
- Multiple injuries
- Abdominal pain upper
- Acute respiratory failure
- Alcohol use
- Anaemia (lack of blood)
- Arrhythmia (irregular heartbeat)
- Blood thyroid stimulating hormone increased
- Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
- Burning sensation
40-49:
- Injury
- Pain
- Abdominal pain upper
- Arthralgia (joint pain)
- Blood ethanol increased
- Blood glucose increased
- Blood thyroid stimulating hormone increased
- Brain natriuretic peptide increased
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
- Cardiac failure congestive
50-59:
- Chest pain
- Confusional state
- Haemorrhoids (a swollen vein or group of veins in the region of the anus)
- Hypertensive heart disease
- Nausea (feeling of having an urge to vomit)
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Vomiting
- Weight decreased
- Acute respiratory failure
- Cardiac failure congestive
60+:
- Dyspnoea (difficult or laboured respiration)
- Cardiac failure congestive
- Arthralgia (joint pain)
- Asthenia (weakness)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hyperlipidaemia (presence of excess lipids in the blood)
- Pneumonia
- Renal failure (kidney dysfunction)
- Weight increased
- Anxiety
What are the existing conditions these people have? *
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 19 people, 19.39%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 13 people, 13.27%
- High Blood Cholesterol: 11 people, 11.22%
- Diabetes: 9 people, 9.18%
- Pain: 6 people, 6.12%
- Hypersensitivity: 6 people, 6.12%
- Cough: 6 people, 6.12%
- Insomnia (sleeplessness): 5 people, 5.10%
- Depression: 5 people, 5.10%
* Approximation only. Some reports may have incomplete information.
Do you take Combivent and Lotensin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Combivent and Lotensin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Combivent:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lotensin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Combivent and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lotensin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on albuterol sulfate; ipratropium bromide and benazepril hydrochloride (the active ingredients of Combivent and Lotensin, respectively), and Combivent and Lotensin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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