Combivir and Ceftriaxone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Combivir (lamivudine; zidovudine) and Ceftriaxone (ceftriaxone sodium). Common drug interactions include drug exposure during pregnancy among females and anhedonia among males.
The phase IV clinical study analyzes what interactions people have when they take Combivir and Ceftriaxone. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.
What is Combivir?
Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.
What is Ceftriaxone?
Ceftriaxone has active ingredients of ceftriaxone sodium. It is often used in typhoid fever. eHealthMe is studying from 40,991 Ceftriaxone users. Check the latest studies of Ceftriaxone.
54 people who take Combivir and Ceftriaxone together, and have interactions are studied.

What are the common drug interactions of Combivir and Ceftriaxone, by gender? *:
female:
- Drug exposure during pregnancy
- Duodenal ulcer
- Emotional distress
- Escherichia infection (bacterial infection by escherichia coli)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Gastrointestinal infection (infection of stomach and intestine)
- Oedema lower limb (fluid collection in tissue of lower leg)
- Oesophageal candidiasis (fungal infection of oesophagus)
- Pain
- Pyelonephritis (inflammation of kidney caused by bacteria)
male:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Renal impairment (severely reduced kidney function)
- Drug exposure during pregnancy
- Osteoporosis (bones weak and more likely to break)
- Hypertension (high blood pressure)
- Tooth fracture
- Back pain
- Cerebral haemorrhage (bleeding within the brain)
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
What are the common drug interactions of Combivir and Ceftriaxone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Pyrexia (fever)
- Abdominal pain
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
- Blood triglycerides increased
- Diarrhoea
- Drug hypersensitivity
- Renal failure (kidney dysfunction)
30-39:
- Anaemia (lack of blood)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Complications of maternal exposure to therapeutic drugs
- Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
- Epidermal necrolysis (skin condition that is usually caused by a reaction to drugs)
- Foetal distress syndrome (altered heart rate or rhythm and leading tocompromised blood flow or changes in blood chemistry of foetus)
- Hepatic function abnormal
- Hepatocellular damage (liver damage)
- Leukopenia (less number of white blood cells in blood)
- Mouth ulceration (mouth ulcers)
40-49:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Emotional distress
- Pain
- Anaemia (lack of blood)
- Back pain
- Bone density decreased
- Chronic kidney disease
- Dysstasia (difficulty in standing)
- Hypertension (high blood pressure)
50-59:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Bone density decreased
- Emotional distress
- Pain
- Tooth loss
- Osteopenia (a condition where bone mineral density is lower than normal)
- Osteoporosis (bones weak and more likely to break)
- Renal impairment (severely reduced kidney function)
- Tooth fracture
60+:
- Pneumonia
- Hepatitis (inflammation of the liver)
- Herpes simplex (herpes simplex is a common viral infection)
- Leukopenia (less number of white blood cells in blood)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Oedema lower limb (fluid collection in tissue of lower leg)
- Oesophageal candidiasis (fungal infection of oesophagus)
- Oesophagitis (inflammation of oesophagus)
- Pyrexia (fever)
- White blood cell count decreased
What are the existing conditions these people have? *
- Hiv Infection: 31 people, 57.41%
- Pain: 4 people, 7.41%
- Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 3 people, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Combivir and Ceftriaxone?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Combivir (15,450 reports)
- Ceftriaxone (40,991 reports)
Browse all drug interactions of Combivir and Ceftriaxone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Combivir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ceftriaxone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Combivir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ceftriaxone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on lamivudine; zidovudine and ceftriaxone sodium (the active ingredients of Combivir and Ceftriaxone, respectively), and Combivir and Ceftriaxone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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