Combivir and Klonopin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Combivir (lamivudine; zidovudine) and Klonopin (clonazepam). Common drug interactions include gout among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Combivir and Klonopin. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Combivir?

Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.

What is Klonopin?

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 65,112 Klonopin users. Check the latest studies of Klonopin.

On Jul, 13, 2026

51 people who take Combivir and Klonopin together, and have interactions are studied.

Combivir and Klonopin drug interactions.

What are the common drug interactions of Combivir and Klonopin, by gender? *:

female:

Gout (uric acid crystals building up in the body)
Hand fracture
Headache (pain in head)
Pancreatitis acute (sudden inflammation of pancreas)
Renal failure (kidney dysfunction)
Sinus bradycardia (an unusually slow heartbeat due to heart disease)
Syncope (loss of consciousness with an inability to maintain postural tone)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Blood cholesterol increased

male:

Emotional distress
Pain
Osteoporosis (bones weak and more likely to break)
Proteinuria (presence of protein in the urine)
Quality of life decreased
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hyperkalaemia (damage to or disease of the kidney)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Impaired work ability

What are the common drug interactions of Combivir and Klonopin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain
Drug screen positive
Transaminases increased
Abdominal distension
Abnormal dreams
Blood creatinine increased
Blood urea increased
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diarrhoea

40-49:

Hypersensitivity
Ileus (a painful obstruction of the ileum or other part of the intestine)
Intervertebral disc degeneration (spinal disc degeneration)
Loose tooth
Multiple fractures
Oropharyngeal plaque (hard deposit on oropharynx)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Pancreatitis (inflammation of pancreas)

50-59:

Osteoporosis (bones weak and more likely to break)
Proteinuria (presence of protein in the urine)
Quality of life decreased
Back pain
Depression
Osteonecrosis (death of bone)
Asthenia (weakness)
Gait disturbance
Gout (uric acid crystals building up in the body)
Oedema peripheral (superficial swelling)

60+:

Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Sinus congestion (blockage of sinus)
Vomiting

What are the existing conditions these people have? *

Hiv Infection: 30 people, 58.82%
High Blood Pressure: 12 people, 23.53%
Depression: 10 people, 19.61%
Pain: 8 people, 15.69%
Asthma: 5 people, 9.80%
Gastric Ulcer (stomach ulcer): 5 people, 9.80%
Bacterial Infection: 4 people, 7.84%
Chest Pain: 4 people, 7.84%
Constipation: 4 people, 7.84%
Diabetes: 4 people, 7.84%

* Approximation only. Some reports may have incomplete information.

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