Combivir and Nitrostat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Combivir (lamivudine; zidovudine) and Nitrostat (nitroglycerin). Common drug interactions include emotional distress among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Combivir and Nitrostat. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Combivir?

Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.

What is Nitrostat?

Nitrostat has active ingredients of nitroglycerin. It is often used in chest pain. eHealthMe is studying from 14,082 Nitrostat users. Check the latest studies of Nitrostat.

On Aug, 02, 2026

27 people who take Combivir and Nitrostat together, and have interactions are studied.

Combivir and Nitrostat drug interactions.

What are the common drug interactions of Combivir and Nitrostat, by gender? *:

female:

Emotional distress
Pain
Alopecia (absence of hair from areas of the body)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Blood creatinine increased
Bone density decreased
Chronic kidney disease
Depression

male:

Chronic kidney disease
Anxiety
Depression
Renal failure (kidney dysfunction)
Bone density decreased
Decreased activity
Pain in extremity
Proteinuria (presence of protein in the urine)
Quality of life decreased
Bone pain

What are the common drug interactions of Combivir and Nitrostat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Neutropenia (an abnormally low number of neutrophils)
Pneumonia

30-39:

n/a

40-49:

Chronic kidney disease
Gait disturbance
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Bone pain
Drug resistance (reduction in effectiveness of a drug)
Renal impairment (severely reduced kidney function)

50-59:

Anxiety
Chronic kidney disease
Emotional distress
Pain
Fatigue (feeling of tiredness)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Osteoporosis (bones weak and more likely to break)
Depression
Decreased activity
Gait disturbance

60+:

Blood creatinine increased
Chronic kidney disease
Renal disorder (kidney disease)
Renal impairment (severely reduced kidney function)
Renal tubular disorder (disease of kidney tubules)
Drug ineffective
Lumbar vertebral fracture
Multiple fractures
Nephropathy (damage to or disease of a kidney)
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)

What are the existing conditions these people have? *

Hiv Infection: 19 people, 70.37%
Pain: 8 people, 29.63%
Depression: 6 people, 22.22%
High Blood Pressure: 6 people, 22.22%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 22.22%
Constipation: 6 people, 22.22%
Insomnia (sleeplessness): 4 people, 14.81%
Stress And Anxiety: 4 people, 14.81%
Prostatomegaly (enlargement of the prostate): 4 people, 14.81%
Panic Disorder: 4 people, 14.81%

* Approximation only. Some reports may have incomplete information.

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