Cometriq and Alprazolam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cometriq (cabozantinib s-malate) and Alprazolam (alprazolam). Common drug interactions include vomiting among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Cometriq and Alprazolam. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Cometriq?

Cometriq has active ingredients of cabozantinib s-malate. eHealthMe is studying from 2,712 Cometriq users. Check the latest studies of Cometriq.

What is Alprazolam?

Alprazolam has active ingredients of alprazolam. It is often used in stress and anxiety. eHealthMe is studying from 134,864 Alprazolam users. Check the latest studies of Alprazolam.

On Aug, 08, 2026

27 people who take Cometriq and Alprazolam together, and have interactions are studied.

Cometriq and Alprazolam drug interactions.

What are the common drug interactions of Cometriq and Alprazolam, by gender? *:

female:

Vomiting
Diarrhoea
Nausea (feeling of having an urge to vomit)
Blood pressure increased
Abdominal pain
Stomatitis (inflammation of mucous membrane of mouth)
Cough
Decreased appetite
Dysgeusia (disorder of the sense of taste)
Dysphonia (speech disorder attributable to a disorder of phonation)

male:

Diarrhoea
Infection
Lip pain
Neuralgia (pain in one or more nerves)
Oral pain
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Sinusitis (inflammation of sinus)
Cardiac failure
Cough

What are the common drug interactions of Cometriq and Alprazolam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Lip pain
Oral pain
Sinusitis (inflammation of sinus)

40-49:

n/a

50-59:

Abdominal discomfort
Dehydration (dryness resulting from the removal of water)
Hypophagia (reduced food intake)
Nausea (feeling of having an urge to vomit)
Vomiting
Abdominal distension
Blood pressure increased
Death
Diarrhoea
Dysphonia (speech disorder attributable to a disorder of phonation)

60+:

Diarrhoea
Blood pressure increased
Blood glucose increased
Chills (felling of cold)
Cold sweat
Constipation
Death
Decreased appetite
Dysgeusia (disorder of the sense of taste)
Eating disorder

What are the existing conditions these people have? *

Thyroid Cancer: 13 people, 48.15%
Renal Cell Carcinoma (a kidney cancer): 5 people, 18.52%
Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 4 people, 14.81%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 7.41%
Connective Tissue Neoplasm (tumour of connective tissue): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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