Dexamethasone and Fycompa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dexamethasone (dexamethasone) and Fycompa (perampanel). Common drug interactions include cytokine release syndrome among females and blood pressure increased among males.

The phase IV clinical study analyzes what interactions people have when they take Dexamethasone and Fycompa. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Dexamethasone?

Dexamethasone has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 161,927 Dexamethasone users. Check the latest studies of Dexamethasone.

What is Fycompa?

Fycompa has active ingredients of perampanel. eHealthMe is studying from 4,387 Fycompa users. Check the latest studies of Fycompa.



On Aug, 08, 2026

13 people who take Dexamethasone and Fycompa together, and have interactions are studied.

Dexamethasone and Fycompa drug interactions.

What are the common drug interactions of Dexamethasone and Fycompa, by gender? *:

female:

  1. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  2. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  3. Leukoencephalopathy (disease of the white matter in the brain)
  4. Pancreatitis (inflammation of pancreas)
  5. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  6. Rash macular (small, flat red spots)
  7. Spinal compression fracture (fracture due to spinal compression on bone)

male:

  1. Blood pressure increased
  2. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  3. Tic (a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups)
  4. Anaemia (lack of blood)
  5. Blood sodium decreased
  6. Body temperature increased
  7. Clonic convulsion (long lasting seizure)
  8. Death
  9. Fatigue (feeling of tiredness)
  10. Flushing (the warm, red condition of human skin)

What are the common drug interactions of Dexamethasone and Fycompa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  3. Tic (a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups)

20-29:

n/a

30-39:

  1. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  2. Conversion disorder (neurological symptoms, such as numbness, blindness, paralysis, or fits without a definable organic cause)
  3. Headache (pain in head)
  4. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  5. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  6. Leukoencephalopathy (disease of the white matter in the brain)
  7. Pancreatitis (inflammation of pancreas)
  8. Blood pressure increased

40-49:

  1. Suicide attempt

50-59:

  1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  2. Rash macular (small, flat red spots)

60+:

  1. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  2. Blood pressure increased
  3. Blood pressure systolic increased
  4. Pneumonia
  5. Weight increased
  6. Spinal compression fracture (fracture due to spinal compression on bone)

What are the existing conditions these people have? *

  1. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 5 people, 38.46%
  2. Pneumonia: 3 people, 23.08%
  3. Fever: 3 people, 23.08%
  4. Encephalitis (inflammation of the brain): 3 people, 23.08%
  5. Pemphigoid (tense blisters on the skin): 1 person, 7.69%
  6. Partial Seizures (seizures which affect only a part of the brain at onset): 1 person, 7.69%
  7. Immunodeficiency: 1 person, 7.69%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 7.69%
  9. High Blood Pressure: 1 person, 7.69%
  10. Glioma (a type of tumour that starts in the brain or spine): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Dexamethasone and Fycompa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dexamethasone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Fycompa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dexamethasone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fycompa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dexamethasone and perampanel (the active ingredients of Dexamethasone and Fycompa, respectively), and Dexamethasone and Fycompa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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