Compazine and Vimpat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Compazine (prochlorperazine maleate) and Vimpat (lacosamide). Common drug interactions include erythema among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Compazine and Vimpat. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

What is Vimpat?

Vimpat has active ingredients of lacosamide. It is often used in epilepsy. eHealthMe is studying from 20,831 Vimpat users. Check the latest studies of Vimpat.

On Jul, 13, 2026

26 people who take Compazine and Vimpat together, and have interactions are studied.

What are the common drug interactions of Compazine and Vimpat, by gender? *:

female:

Erythema (redness of the skin)
Gait disturbance
Gastric disorder (disease of stomach)
Haemorrhage intracranial (bleeding within the skull)
Haemorrhagic diathesis (bleeding tendency)
Hallucination (an experience involving the perception of something not present)
Hypertension (high blood pressure)
Hypervolaemia (abnormally increased volume of blood)
Interstitial lung disease
Intestinal obstruction

male:

Headache (pain in head)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Hypoaesthesia (reduced sense of touch or sensation)
Intervertebral disc degeneration (spinal disc degeneration)
Intervertebral disc protrusion (spinal disc protrusion)
Memory impairment
Muscular weakness (muscle weakness)
Neuropathy peripheral (surface nerve damage)
Rash erythematous (redness of the skin)
Rash pruritic (redness with itching)

What are the common drug interactions of Compazine and Vimpat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Blood glucose increased

30-39:

Breast cancer stage iii
Glioblastoma (most common and most aggressive malignant primary brain tumour in humans)

40-49:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Ataxia (loss of full control of bodily movements)
Balance disorder
Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Cerebral atrophy (decrement in size of brain)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dizziness
Dysarthria (speech disorder)
Gait disturbance
Headache (pain in head)

50-59:

Haematocrit decreased
Haemoglobin decreased
Hepatic failure (liver failure)
Hypersensitivity
Immunosuppressant drug level decreased
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Skin disorder (skin disease)

60+:

Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
Abdominal discomfort
Abdominal pain
Adverse reaction
Anaphylactic reaction (serious allergic reaction)
Appetite disorder (abnormal eating habits)
Arthralgia (joint pain)
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Back pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 8 people, 30.77%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 23.08%
Pain: 5 people, 19.23%
Fungal Infection: 4 people, 15.38%
Abdominal Discomfort: 3 people, 11.54%
Headache (pain in head): 3 people, 11.54%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 3 people, 11.54%
Constipation: 3 people, 11.54%
Leukaemia (blood or bone marrow cancer): 3 people, 11.54%
Stomatitis (inflammation of mucous membrane of mouth): 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

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