Compazine and Xeljanz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Compazine (prochlorperazine maleate) and Xeljanz (tofacitinib citrate). Common drug interactions include weight decreased among females and bronchitis among males.

The phase IV clinical study analyzes what interactions people have when they take Compazine and Xeljanz. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

What is Xeljanz?

Xeljanz has active ingredients of tofacitinib citrate. It is often used in rheumatoid arthritis. eHealthMe is studying from 239,081 Xeljanz users. Check the latest studies of Xeljanz.

On Jul, 19, 2026

30 people who take Compazine and Xeljanz together, and have interactions are studied.

Compazine and Xeljanz drug interactions.

What are the common drug interactions of Compazine and Xeljanz, by gender? *:

female:

Weight decreased
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Drug hypersensitivity
Alopecia (absence of hair from areas of the body)
Anxiety
Drug intolerance (drug sensitivity)
Feeling jittery
Increased appetite
Intervertebral disc degeneration (spinal disc degeneration)
Neuropathy peripheral (surface nerve damage)

male:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Contusion (a type of hematoma of tissue in which capillaries)
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Poor venous access
Fall
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Infusion related reaction
Migraine (headache)
Skin irritation
Surgery

What are the common drug interactions of Compazine and Xeljanz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Acne (skin problems that cause pimples)
Drug hypersensitivity
Influenza like illness
Crying
Depressed mood
Fatigue (feeling of tiredness)
Fear
Feelings of worthlessness
Malaise (a feeling of general discomfort or uneasiness)
Mood altered (changes in mood)

50-59:

Dysphagia (a condition in which swallowing is difficult or painful)
Eyelid ptosis (falling of the upper or lower eyelid)
Food allergy
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Milk allergy
Muscular weakness (muscle weakness)
Mycotic allergy (fungal allergy)
Respiratory failure (inadequate gas exchange by the respiratory system)
Blood pressure increased
Bone pain

60+:

Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Weight decreased
Pelvic fracture
Peripheral nerve lesion
Spinal column stenosis (narrowing of spinal column)
Urinary tract infection
Sleep disorder
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Infusion related reaction

What are the existing conditions these people have? *

Weight Decreased: 6 people, 20.00%
Pain In Jaw: 6 people, 20.00%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 16.67%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 4 people, 13.33%
Pain: 4 people, 13.33%
Nausea (feeling of having an urge to vomit): 3 people, 10.00%
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 3 people, 10.00%
Stress And Anxiety: 3 people, 10.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.67%
Asthma: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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