Comtan and Klor-con drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Comtan (entacapone) and Klor-con (potassium chloride). Common drug interactions include depression among females and hallucination among males.

The phase IV clinical study analyzes what interactions people have when they take Comtan and Klor-con. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Comtan?

Comtan has active ingredients of entacapone. It is often used in parkinson's disease. eHealthMe is studying from 3,979 Comtan users. Check the latest studies of Comtan.

What is Klor-con?

Klor-con has active ingredients of potassium chloride. It is often used in hypokalemia. eHealthMe is studying from 27,547 Klor-con users. Check the latest studies of Klor-con.

On Jul, 16, 2026

26 people who take Comtan and Klor-con together, and have interactions are studied.

What are the common drug interactions of Comtan and Klor-Con, by gender? *:

female:

Depression
Pathological gambling
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Chest pain
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Coronary artery stenosis (narrowing of coronary artery)
Dehydration (dryness resulting from the removal of water)
Electrocardiogram repolarisation abnormality
Groin pain
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

male:

Hallucination (an experience involving the perception of something not present)
Hypotension (abnormally low blood pressure)
Nonspecific reaction (unspecified reaction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Seasonal allergy (allergic condition due to certain season)
Sepsis (a severe blood infection that can lead to organ failure and death)
Urinary tract infection
Infusion related reaction
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Death

What are the common drug interactions of Comtan and Klor-Con, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Fatigue (feeling of tiredness)

60+:

Hallucination (an experience involving the perception of something not present)
Hypotension (abnormally low blood pressure)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Normochromic normocytic anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)
Renal failure acute (rapid kidney dysfunction)
Thrombocytopenia (decrease of platelets in blood)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Blood creatine increased

What are the existing conditions these people have? *

Hallucinations (sensations that appear real but are created by your mind): 6 people, 23.08%
Pain: 4 people, 15.38%
Urinary Tract Infection: 3 people, 11.54%
Stress And Anxiety: 3 people, 11.54%
Seasonal Allergy (allergic condition due to certain season): 3 people, 11.54%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 3 people, 11.54%
Oedema (fluid collection in tissue): 3 people, 11.54%
Insomnia (sleeplessness): 3 people, 11.54%
Helicobacter Infection (helicobacter pylori (h. pylori) infects stomach): 3 people, 11.54%
Constipation: 3 people, 11.54%

* Approximation only. Some reports may have incomplete information.

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