Comtan and Omeprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Comtan (entacapone) and Omeprazole (omeprazole). Common drug interactions include dyskinesia among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Comtan and Omeprazole. It is created by eHealthMe based on reports of 90 people who take the same drugs from the FDA, and is updated regularly.

What is Comtan?

Comtan has active ingredients of entacapone. It is often used in parkinson's disease. eHealthMe is studying from 3,979 Comtan users. Check the latest studies of Comtan.

What is Omeprazole?

Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 410,631 Omeprazole users. Check the latest studies of Omeprazole.

On Jul, 12, 2026

90 people who take Comtan and Omeprazole together, and have interactions are studied.

Comtan and Omeprazole drug interactions.

What are the common drug interactions of Comtan and Omeprazole, by gender? *:

female:

Dyskinesia (abnormality or impairment of voluntary movement)
Excessive granulation tissue (excessive collagen-rich tissue which forms at the site of an injury)
Hallucination (an experience involving the perception of something not present)
Limb injury
Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
Muscle rigidity (muscle stiffness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Neoplasm (tumour)
Nerve injury
Oesophageal disorder (disease of oesophagus)

male:

Fall
Hallucination (an experience involving the perception of something not present)
Diarrhoea
Hallucination, auditory (perceiving sounds without auditory stimulus)
Hospitalisation
Ligament rupture (tear in ligament)
Screaming (a long loud piercing cry)
Neoplasm malignant (cancer tumour)
Syncope (loss of consciousness with an inability to maintain postural tone)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the common drug interactions of Comtan and Omeprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease

50-59:

Weight decreased
Fall
Asthenia (weakness)
Drug ineffective
Muscle rigidity (muscle stiffness)
Pain
Abdominal rigidity
Back pain
Blood pressure fluctuation
Intervertebral disc protrusion (spinal disc protrusion)

60+:

Pneumonia
Fall
Ligament rupture (tear in ligament)
Screaming (a long loud piercing cry)
Tremor (trembling or shaking movements in one or more parts of your body)
Urinary tract infection
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Death
Hospitalisation
Neoplasm malignant (cancer tumour)

What are the existing conditions these people have? *

Pain: 14 people, 15.56%
Constipation: 10 people, 11.11%
Insomnia (sleeplessness): 9 people, 10.00%
High Blood Pressure: 9 people, 10.00%
Sleep Disorder: 7 people, 7.78%
High Blood Cholesterol: 7 people, 7.78%
Hallucinations (sensations that appear real but are created by your mind): 6 people, 6.67%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 6.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 5.56%
Osteoporosis (bones weak and more likely to break): 5 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Comtan and Omeprazole?

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