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Copegus and Tracleer drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Copegus (ribavirin) and Tracleer (bosentan). Common drug interactions include alanine aminotransferase increased among females and balance disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Copegus and Tracleer. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Copegus?

Copegus has active ingredients of ribavirin. It is often used in hepatitis c. eHealthMe is studying from 15,115 Copegus users. Check the latest studies of Copegus.

What is Tracleer?

Tracleer has active ingredients of bosentan. It is often used in primary pulmonary hypertension. eHealthMe is studying from 55,125 Tracleer users. Check the latest studies of Tracleer.

On Jul, 19, 2026

11 people who take Copegus and Tracleer together, and have interactions are studied.

Copegus and Tracleer drug interactions.

What are the common drug interactions of Copegus and Tracleer, by gender? *:

female:

  1. Alanine aminotransferase increased
  2. Aspartate aminotransferase increased
  3. Dizziness
  4. Fall
  5. Hypotension (abnormally low blood pressure)
  6. Balance disorder
  7. Blood bilirubin increased
  8. Confusional state
  9. Diarrhoea
  10. Drug level increased

male:

  1. Balance disorder
  2. Confusional state
  3. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  4. Drug hypersensitivity
  5. Pneumonia
  6. Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
  7. Respiratory distress (difficulty in breathing)
  8. Dizziness
  9. Dyspnoea (difficult or laboured respiration)
  10. Gait disturbance

What are the common drug interactions of Copegus and Tracleer, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Balance disorder
  2. Confusional state
  3. Fall
  4. Nausea (feeling of having an urge to vomit)
  5. Diarrhoea
  6. Drug level increased
  7. Asthenia (weakness)
  8. Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)
  9. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  10. Vertigo

60+:

  1. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  2. Drug hypersensitivity
  3. Fall
  4. Hypotension (abnormally low blood pressure)
  5. Hypoxia (low oxygen in tissues)
  6. Injury
  7. Loss of consciousness
  8. Lower limb fracture
  9. Presyncope
  10. Swelling

What are the existing conditions these people have? *

  1. Hiv Infection: 3 people, 27.27%
  2. Diarrhea: 3 people, 27.27%
  3. Idiopathic Pulmonary Fibrosis (chronic lung disease): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Copegus and Tracleer?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Copegus and Tracleer:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Copegus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tracleer:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Copegus and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tracleer and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on ribavirin and bosentan (the active ingredients of Copegus and Tracleer, respectively), and Copegus and Tracleer (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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