Subutex and Dexilant drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Subutex (buprenorphine hydrochloride) and Dexilant (dexlansoprazole). Common drug interactions include acute coronary syndrome among females and acute respiratory distress syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Subutex and Dexilant. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Subutex?

Subutex has active ingredients of buprenorphine hydrochloride. It is often used in opiate withdrawal. eHealthMe is studying from 8,763 Subutex users. Check the latest studies of Subutex.

What is Dexilant?

Dexilant has active ingredients of dexlansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 57,103 Dexilant users. Check the latest studies of Dexilant.

On Jul, 19, 2026

13 people who take Subutex and Dexilant together, and have interactions are studied.

What are the common drug interactions of Subutex and Dexilant, by gender? *:

female:

Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Acute left ventricular failure (heart attack)
Acute respiratory failure
Chronic kidney disease

male:

Acute respiratory distress syndrome
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dyspnoea (difficult or laboured respiration)
Hyperhidrosis (abnormally increased sweating)
Listless (lack of interest, energy, or spirit)
Malaise (a feeling of general discomfort or uneasiness)
Pulse absent
Skin discolouration (change of skin colour)
Soliloquy
Somnolence (a state of near-sleep, a strong desire for sleep)

What are the common drug interactions of Subutex and Dexilant, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Acute respiratory distress syndrome
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dyspnoea (difficult or laboured respiration)
Hyperhidrosis (abnormally increased sweating)
Listless (lack of interest, energy, or spirit)
Malaise (a feeling of general discomfort or uneasiness)
Pulse absent
Skin discolouration (change of skin colour)
Soliloquy
Somnolence (a state of near-sleep, a strong desire for sleep)

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Vulvovaginal Mycotic Infection (vulvovaginal fungal infection): 1 person, 7.69%
Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 7.69%
Diabetic Nephropathy (diabetic kidney disease): 1 person, 7.69%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 1 person, 7.69%
Dizziness: 1 person, 7.69%
Drug Dependence: 1 person, 7.69%
Dry Skin: 1 person, 7.69%
Dysmenorrhea (painful menstruation): 1 person, 7.69%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 1 person, 7.69%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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