Cordarone and Keflex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cordarone (amiodarone hydrochloride) and Keflex (cephalexin). Common drug interactions include back pain among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Cordarone and Keflex. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Cordarone?

Cordarone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 22,776 Cordarone users. Check the latest studies of Cordarone.

What is Keflex?

Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 15,844 Keflex users. Check the latest studies of Keflex.

On Aug, 12, 2026

29 people who take Cordarone and Keflex together, and have interactions are studied.

What are the common drug interactions of Cordarone and Keflex, by gender? *:

female:

Back pain
Balance disorder
Cardiac arrest
Cardiac failure congestive
Carotid artery aneurysm (a bulging or ballooning in the wall of a blood vessel)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Constipation
Dizziness
Dysphonia (speech disorder attributable to a disorder of phonation)
Fall

male:

Dyspnoea (difficult or laboured respiration)
Bladder disorder
Aortic valve sclerosis (narrowing of the aortic valve)
Candidiasis (candidiasis or thrush is a fungal infection)
Carotid artery disease
Chest pain
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Dyspepsia (indigestion)
Flushing (the warm, red condition of human skin)
Groin pain

What are the common drug interactions of Cordarone and Keflex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Cardiac disorder
Cardiac failure congestive
Chest pain
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Diabetic foot ulcer
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Electrocardiogram abnormal
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)

60+:

Dizziness
Cardiac arrest
Otitis externa (external ear infection)
Rectal haemorrhage (bleeding from anus)
Rhinitis allergic (inflammation of the nasal airways due to allergy)
Upper respiratory tract infection
Adenoma benign (non-cancerous tumour -secreting)
Aortic valve sclerosis (narrowing of the aortic valve)
Bladder disorder
Candidiasis (candidiasis or thrush is a fungal infection)

What are the existing conditions these people have? *

Vitamin D Decreased: 6 people, 20.69%
Sleep Disorder: 6 people, 20.69%
Rashes (redness): 6 people, 20.69%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 6 people, 20.69%
Indigestion: 6 people, 20.69%
High Blood Pressure: 6 people, 20.69%
Cellulitis (infection under the skin): 6 people, 20.69%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 17.24%

* Approximation only. Some reports may have incomplete information.

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