Cordarone and Tapazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cordarone (amiodarone hydrochloride) and Tapazole (methimazole). Common drug interactions include pancreatic mass among females and pneumonitis among males.

The phase IV clinical study analyzes what interactions people have when they take Cordarone and Tapazole. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Cordarone?

Cordarone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 22,776 Cordarone users. Check the latest studies of Cordarone.

What is Tapazole?

Tapazole has active ingredients of methimazole. It is often used in hyperthyroidism. eHealthMe is studying from 2,477 Tapazole users. Check the latest studies of Tapazole.

On Jul, 15, 2026

26 people who take Cordarone and Tapazole together, and have interactions are studied.

Cordarone and Tapazole drug interactions.

What are the common drug interactions of Cordarone and Tapazole, by gender? *:

female:

Pancreatic mass
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Peripheral vascular disorder
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Renal cyst (kidney cyst)
Renal failure acute (rapid kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Respiratory failure (inadequate gas exchange by the respiratory system)
Loss of consciousness

male:

Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Drug ineffective
Haematoma (collection of blood outside the blood vessels)
Headache (pain in head)
Hypotension (abnormally low blood pressure)
Mitral valve disease (disease of mitral valve of heart)
Pyrexia (fever)
Refractory anaemia (an anaemia which does not respond to treatment)
Rigors (an episode of shaking or exaggerated shivering)
Tricuspid valve disease (disease of heart valve)

What are the common drug interactions of Cordarone and Tapazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Blood thyroid stimulating hormone decreased
Influenza

40-49:

n/a

50-59:

Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)

60+:

Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Drug ineffective
Cardiac disorder
Haematemesis (vomiting of blood)
Haematoma (collection of blood outside the blood vessels)
Headache (pain in head)
Hepatic enzyme increased
Hypotension (abnormally low blood pressure)
International normalised ratio increased
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 30.77%
Lung Cancer - Non-Small Cell (lung cancer): 6 people, 23.08%
Dyslipidaemia (abnormal amount of lipids): 6 people, 23.08%
Multiple Myeloma (cancer of the plasma cells): 2 people, 7.69%
Indigestion: 2 people, 7.69%
Blood Pressure Abnormal: 2 people, 7.69%
Arrhythmias (irregular heartbeat): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Cordarone and Tapazole?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously