Actonel and Ciprofloxacin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Actonel (risedronate sodium) and Ciprofloxacin (ciprofloxacin). Common drug interactions include malaise among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Actonel and Ciprofloxacin. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.

What is Ciprofloxacin?

Ciprofloxacin has active ingredients of ciprofloxacin. It is often used in urinary tract infection. eHealthMe is studying from 22,256 Ciprofloxacin users. Check the latest studies of Ciprofloxacin.

On Jul, 15, 2026

63 people who take Actonel and Ciprofloxacin together, and have interactions are studied.

Actonel and Ciprofloxacin drug interactions.

What are the common drug interactions of Actonel and Ciprofloxacin, by gender? *:

female:

Malaise (a feeling of general discomfort or uneasiness)
Respiratory tract infection
Wheezing (a high-pitched whistling sound made while you breath)
Nasal oedema (fluid collection in nose)
Oedema (fluid collection in tissue)
Interstitial lung disease
Abdominal pain
Arthralgia (joint pain)
C-reactive protein increased
Fall

male:

Anxiety
Arthralgia (joint pain)
Fistula discharge (discharge from abnormal passage of structure/organ)
Gait disturbance
Injury
Intestinal obstruction
Small intestinal obstruction (blockage in small intestine)
Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button)
Back pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)

What are the common drug interactions of Actonel and Ciprofloxacin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pulmonary embolism (blockage of the main artery of the lung)

40-49:

Pyelonephritis acute (sudden inflammation of kidney caused by bacteria)

50-59:

Back pain
Bipolar disorder (mood disorder)
Blast cell count increased
Bone disorder
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
C-reactive protein increased
Carotid artery disease
Cellulitis (infection under the skin)

60+:

Pain
Pneumonia
Respiratory tract infection
Wheezing (a high-pitched whistling sound made while you breath)
Oedema (fluid collection in tissue)
Arthralgia (joint pain)
Interstitial lung disease
Wound
Abdominal pain
Fall

What are the existing conditions these people have? *

Wheezing (a high-pitched whistling sound made while you breath): 34 people, 53.97%
Asthma: 34 people, 53.97%
Cough: 30 people, 47.62%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 9.52%
High Blood Pressure: 5 people, 7.94%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 7.94%
Respiratory Tract Infection: 4 people, 6.35%
Pneumonia: 4 people, 6.35%
Pain: 4 people, 6.35%

* Approximation only. Some reports may have incomplete information.

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