Cordarone and Tracrium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cordarone (amiodarone hydrochloride) and Tracrium (atracurium besylate). Common drug interactions include extubation among females and coombs negative haemolytic anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Cordarone and Tracrium. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Cordarone?

Cordarone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 22,776 Cordarone users. Check the latest studies of Cordarone.

What is Tracrium?

Tracrium has active ingredients of atracurium besylate. eHealthMe is studying from 909 Tracrium users. Check the latest studies of Tracrium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

21 people who take Cordarone and Tracrium together, and have interactions are studied.

Cordarone and Tracrium drug interactions.

What are the common drug interactions of Cordarone and Tracrium, by gender? *:

female:

Extubation
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Brain death
Cerebral haematoma (collection of blood in brain)
Hepatocellular injury (liver injury)
Hyperbilirubinaemia (excess of bilirubin in the blood)

male:

Coombs negative haemolytic anaemia
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Pulmonary oedema (fluid accumulation in the lungs)
Respiratory distress (difficulty in breathing)
Sepsis (a severe blood infection that can lead to organ failure and death)
Acute pulmonary oedema (sudden deposit of fluid in the lung))
Acute respiratory distress syndrome
Acute respiratory failure
Agitation (state of anxiety or nervous excitement)
Alveolitis (inflammation in the socket of a tooth)

What are the common drug interactions of Cordarone and Tracrium, by age (0-1 to 60+)? *:

0-1:

Acute pulmonary oedema (sudden deposit of fluid in the lung))
Agitation (state of anxiety or nervous excitement)
Alveolitis (inflammation in the socket of a tooth)
Bronchopneumopathy
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
Ejection fraction (the percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat)
Electrocardiogram qrs complex prolonged
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haemodynamic instability (disturbances in the blood movement in our body)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Extubation

50-59:

Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Brain death
Cerebral haematoma (collection of blood in brain)

60+:

Coombs negative haemolytic anaemia
Atelectasis (partial or complete collapse of the lung)
Respiratory distress (difficulty in breathing)
Sepsis (a severe blood infection that can lead to organ failure and death)
Acute respiratory distress syndrome
Acute respiratory failure
Cardiac arrest
Cardiomegaly (increased size of heart than normal)
Citrate toxicity
Creatinine renal clearance decreased

What are the existing conditions these people have? *

Sedation: 3 people, 14.29%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 2 people, 9.52%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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