Coreg and Aldara drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Coreg (carvedilol) and Aldara (imiquimod). Common drug interactions include myocardial ischaemia among females and atrial fibrillation among males.
The phase IV clinical study analyzes what interactions people have when they take Coreg and Aldara. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Coreg?
Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.
What is Aldara?
Aldara has active ingredients of imiquimod. It is often used in genital warts. eHealthMe is studying from 2,554 Aldara users. Check the latest studies of Aldara.
14 people who take Coreg and Aldara together, and have interactions are studied.

What are the common drug interactions of Coreg and Aldara, by gender? *:
female:
- Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
- Abdominal pain
- Acute left ventricular failure (heart attack)
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Asthenia (weakness)
- Butterfly rash
- Cardiac failure
- Cardiac failure congestive
male:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Dizziness
- Hypokalaemia (low potassium)
- Pleural effusion (water on the lungs)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Thrombocytopenia (decrease of platelets in blood)
- Transaminases increased
- Urinary tract infection
- Vertigo
- Chronic kidney disease
What are the common drug interactions of Coreg and Aldara, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abdominal pain
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Asthenia (weakness)
- Butterfly rash
- Chest pain
- Dizziness
- Hypokalaemia (low potassium)
- Nausea (feeling of having an urge to vomit)
- Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
- Vomiting
30-39:
- Chronic kidney disease
- Dental caries
- Depression
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
40-49:
n/a
50-59:
n/a
60+:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Aspartate aminotransferase increased
- Hypokalaemia (low potassium)
- Pleural effusion (water on the lungs)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Thrombocytopenia (decrease of platelets in blood)
- Transaminases increased
- Urinary tract infection
- Vertigo
- Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
What are the existing conditions these people have? *
- Actinic Keratosis (skin disease due to sun exposure): 4 people, 28.57%
- Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 3 people, 21.43%
- Hypovolaemia (a decreased volume of circulating blood in the body): 3 people, 21.43%
- Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 3 people, 21.43%
- Mineral Deficiency (lack of mineral): 3 people, 21.43%
- Endophthalmitis (inflammation of the internal coats of the eye): 3 people, 21.43%
- Electrolyte Imbalance: 3 people, 21.43%
- Hypotension (abnormally low blood pressure): 3 people, 21.43%
- Diarrhea: 3 people, 21.43%
- Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 3 people, 21.43%
* Approximation only. Some reports may have incomplete information.
Do you take Coreg and Aldara?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Coreg and Aldara:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Coreg:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Aldara:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Coreg and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Aldara and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on carvedilol and imiquimod (the active ingredients of Coreg and Aldara, respectively), and Coreg and Aldara (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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