Coreg and Amantadine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Coreg (carvedilol) and Amantadine (amantadine). Common drug interactions include fall among females and bradycardia among males.
The phase IV clinical study analyzes what interactions people have when they take Coreg and Amantadine. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Coreg?
Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.
What is Amantadine?
Amantadine has active ingredients of amantadine. eHealthMe is studying from 2,261 Amantadine users. Check the latest studies of Amantadine.
19 people who take Coreg and Amantadine together, and have interactions are studied.

What are the common drug interactions of Coreg and Amantadine, by gender? *:
female:
- Fall
- Drug ineffective
- Parkinson's disease
- Urinary tract infection
male:
- Bradycardia (abnormally slow heart action)
- Cardiac failure
- Pulmonary oedema (fluid accumulation in the lungs)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Dyspnoea (difficult or laboured respiration)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Cardiovascular insufficiency (inadequate functioning of heart)
- Death
- Hallucination (an experience involving the perception of something not present)
What are the common drug interactions of Coreg and Amantadine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Bradycardia (abnormally slow heart action)
- Cardiac failure
- Parkinson's disease
- Pulmonary oedema (fluid accumulation in the lungs)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Dyspnoea (difficult or laboured respiration)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Cardiovascular insufficiency (inadequate functioning of heart)
- Death
What are the existing conditions these people have? *
- Parkinson's Disease: 5 people, 26.32%
- Urinary Tract Infection: 1 person, 5.26%
- Urinary Retention (the inability to completely or partially empty the bladder): 1 person, 5.26%
- Pulmonary Congestion (congestion in the lungs): 1 person, 5.26%
- Oedema (fluid collection in tissue): 1 person, 5.26%
- Nausea (feeling of having an urge to vomit): 1 person, 5.26%
- Insomnia (sleeplessness): 1 person, 5.26%
- Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 5.26%
- Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 1 person, 5.26%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Coreg and Amantadine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Coreg (49,583 reports)
- Amantadine (2,261 reports)
Browse all drug interactions of Coreg and Amantadine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Coreg:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Amantadine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Coreg and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Amantadine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on carvedilol and amantadine (the active ingredients of Coreg and Amantadine, respectively), and Coreg and Amantadine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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