Coreg and Combivir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Coreg (carvedilol) and Combivir (lamivudine; zidovudine). Common drug interactions include renal injury among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Coreg and Combivir. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Coreg?

Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.

What is Combivir?

Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.



On Aug, 10, 2026

32 people who take Coreg and Combivir together, and have interactions are studied.

Coreg and Combivir drug interactions.

What are the common drug interactions of Coreg and Combivir, by gender? *:

female:

  1. Renal injury (kidney injury)
  2. Suicidal ideation
  3. Tooth loss
  4. Abdominal pain upper
  5. Abnormal dreams
  6. Anaemia macrocytic (a macrocytic class of anaemia)
  7. Blood pressure inadequately controlled
  8. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  9. Decreased appetite
  10. Exomphalos (weakness of the baby's abdominal wall where the umbilical cord joins it)

male:

  1. Chronic kidney disease
  2. Emotional distress
  3. Fatigue (feeling of tiredness)
  4. Insomnia (sleeplessness)
  5. Multiple injuries
  6. Osteopenia (a condition where bone mineral density is lower than normal)
  7. Quality of life decreased
  8. Sleep disorder
  9. Arthralgia (joint pain)
  10. Asthenia (weakness)

What are the common drug interactions of Coreg and Combivir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anxiety
  2. Blood creatinine increased
  3. Chronic kidney disease
  4. Depression
  5. Renal injury (kidney injury)
  6. Anaemia macrocytic (a macrocytic class of anaemia)
  7. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  8. Electrocardiogram qt corrected interval prolonged
  9. Electrocardiogram qt prolonged
  10. Haemolytic anaemia (anaemia due to haemolysis)

40-49:

  1. Alcohol interaction
  2. Apathy
  3. Asthenia (weakness)
  4. Blood alcohol increased
  5. Dizziness
  6. Fall
  7. Fatigue (feeling of tiredness)
  8. Hyperkalaemia (damage to or disease of the kidney)
  9. Hypotension (abnormally low blood pressure)
  10. Insomnia (sleeplessness)

50-59:

  1. Chronic kidney disease
  2. Emotional distress
  3. Pain
  4. Anxiety
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Renal failure (kidney dysfunction)
  7. Bone density decreased
  8. Depression
  9. Osteopenia (a condition where bone mineral density is lower than normal)
  10. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

60+:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Abnormal dreams
  4. Blood pressure inadequately controlled
  5. Death
  6. Decreased appetite
  7. Ectopic pregnancy (a pregnancy in which the foetus develops outside the uterus, typically in a fallopian tube)
  8. Exomphalos (weakness of the baby's abdominal wall where the umbilical cord joins it)
  9. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  10. Insomnia (sleeplessness)

What are the existing conditions these people have? *

  1. Hiv Infection: 30 people, 93.75%
  2. Muscle Spasms (muscle contraction): 4 people, 12.50%
  3. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 9.38%
  4. High Blood Cholesterol: 3 people, 9.38%
  5. Insomnia (sleeplessness): 3 people, 9.38%
  6. Joint Pain: 3 people, 9.38%
  7. Pain: 3 people, 9.38%
  8. Erection Problems: 3 people, 9.38%
  9. Headache (pain in head): 2 people, 6.25%
  10. Haemolytic Anaemia (anaemia due to haemolysis): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Coreg and Combivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Coreg:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Combivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Coreg and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Combivir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on carvedilol and lamivudine; zidovudine (the active ingredients of Coreg and Combivir, respectively), and Coreg and Combivir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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